Specialty drug billing & coding references

HCPCS, NDC, modifier, ICD-10, payer policy, and Medicare ASP — sourced inline, refreshed quarterly, reviewed by a Certified Professional Coder.

Beovu
brolucizumab-dbll
J0179
wAMD, DME
Briumvi
ublituximab-xiiy
J2329
Relapsing forms of MS (RRMS, active SPMS, CIS — not PPMS)
Cosentyx
secukinumab
J3247
PsA, AS, plaque psoriasis
Entyvio
vedolizumab
J3380
UC, Crohn's disease
Eylea
aflibercept
J0178
wAMD, DME, RVO, mCNV
Eylea HD
aflibercept (8 mg high-dose)
J0177
wAMD, DME, DR, RVO (high-dose formulation)
Humira / biosimilars
adalimumab + Amjevita, Cyltezo, Hadlima, Hyrimoz
J0135 Q5131 Q5126
RA, PsA, AS, Crohn's, UC, plaque psoriasis
Keytruda
pembrolizumab
J9271
Multiple solid tumor & hematologic indications
Lemtrada
alemtuzumab
J0202
Relapsing forms of MS
Lucentis / biosimilars
ranibizumab + Byooviz, Cimerli
J2778 Q5124
wAMD, DME, RVO, mCNV, ROP
Ocrevus
ocrelizumab (IV)
J2350 NDC 50242-0150-01
RRMS, PPMS, SPMS
Ocrevus Zunovo
ocrelizumab and hyaluronidase-ocsq (SC)
J2351 NDC 50242-0554-01
RRMS, PPMS, SPMS (subcutaneous)
Opdivo
nivolumab
J9299
Melanoma, NSCLC, RCC, others
Rituxan / biosimilars
rituximab + Ruxience, Truxima, Riabni
J9312 Q5119 Q5115
NHL, CLL, RA, GPA/MPA
Soliris / biosimilars
eculizumab + Epysqli, Bkemv
J1299 Q5151 Q5152
PNH, aHUS, gMG, NMOSD
Stelara / biosimilars
ustekinumab + Wezlana, Selarsdi, Pyzchiva, Otulfi, +more
J3357 J3358 Q5137 Q5138
PsA, plaque psoriasis, Crohn's, UC
Tyruko
natalizumab-sztn (biosimilar)
Q5134
RRMS, Crohn's disease
Tysabri
natalizumab
J2323
RRMS, Crohn's disease
Ultomiris
ravulizumab-cwvz
J1303
PNH, aHUS, gMG, NMOSD
Vabysmo
faricimab-svoa
J2777
wAMD, DME, RVO

What makes these references different

Quarterly ASP refresh, automated Medicare reimbursement is bound to our underlying CareCost data layer and updates automatically each quarter when CMS publishes new ASP files. No manual edits.
Inline citations to primary sources Every claim links to FDA, CMS, the manufacturer's billing PDF, or the payer's published policy. We do not paraphrase from billing-software vendor blogs.
Reviewed by a Certified Professional Coder Each page is reviewed and signed off by a credentialed coder. Disagreement between manufacturer and payer guidance is surfaced — not hidden.
Per-section freshness dates ASP data, payer policies, code rules, and FDA labels are tracked and stamped per section. When a source goes stale, you'll see it.

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