New and retired HCPCS drug codes, quarter by quarter

Q4 2026 loaded · 38 added · 10 retired · 800 payment limits changed

The Medicare Part B payment-limit file changes every quarter: new J-codes and biosimilar Q-codes appear, discontinued products drop out, and most payment limits move. This page is that diff, quarter by quarter, read straight from the CMS file — the same list the Quarterly Rate Reset sends subscribers.

Reviewed Sep 20, 2026 · maintained by Erin Rose · general reference, not legal advice

How to read this page

CMS publishes the Part B payment-limit file every quarter. A code that appears for the first time is a new HCPCS code — usually a drug that was billed as unclassified (J3490, J3590, C9399) until CMS assigned it a permanent J-code, or a biosimilar getting its Q5 code. A code that drops out is retired: the product was discontinued, folded into another code, or moved off the ASP methodology. On the effective date, claims with the old code start denying and claims with the new one start paying — and the NDC crosswalk moves with it.

The current quarter is expanded below; earlier quarters are collapsed. Codes link to their drug page when this site has one. Payment limits are CMS's published figure per billing unit — ASP + 6% for most drugs; for a biosimilar CMS adds 8% of the reference product's ASP instead, and the IRA inflation rebate lowers some. When a retired code has a successor, the Bill instead column names it and the unit multiplier — a code renumbered from per 500 mg to per 10 mg means the same dose is 50× the units, which is the billing-units trap of every renumbering quarter.

Q4 2026 — current quarter

Effective October 1, 2026 · 38 codes added, 10 retired, 800 payment limits changed vs Q3 2026.

Added in Q4 2026

CodeDescriptorBilling unitPayment limitFamilyReplaces
90616Flu vacc trivalent mRNA IM$171.211CPT
J0014Cocaine hcl nasal (goprelto)1 MG$1.825J-code
J0528Inj fosfomycin disodium 20mg20 MG$0.633J-code
J0643Inj leucovorin calcium 1 mg1 MG$0.054J-codeJ0640 (50 MG, ×50 units)
J0644Inj, leucovorin cal (avyxa)1 MG$2.625J-code
J0716Centruroides immune f(ab)UP TO 120MG$5,449.649J-code
J0841Inj crotalidae im f(ab')2 eq120 MG$1,084.909J-codeback on the file after a gap
J0871Inj, daptomycin (endo) 1mg1 MG$0.541J-code
J1289Narsoplimab-wuug, 1 mg1 MG$105.441J-code
J1577Inj, qivigy, 100mg100 MG$29.280J-code
J1737Inj meloxicam (azurity) 1mg1 MG$1.060J-code
J1957Injection levetiracetam 5 mg5 MG$0.013J-codeJ1953 (10 MG, ×2 units)
J1958Inj levetirac sodi chlo 5 mg5 MG$0.033J-code
J2361Inj depemokimab-ulaa 1 mg1 MG$275.391J-code
J2374Apraclonidine hcl opht 0.1ml0.1 ML$28.804J-code
J2789Riboflavin epioxa/hd<=2mlUP TO 2 ML$41,359.618J-code
J3268Injection, delafloxacin1 MG$0.478J-code
J3404Inj zopapogene per ther dosePer Therapeutic Dose$119,675.512J-code
J3405Inj onase abepar-brve treatPer treatment$2,729,937.922J-code
J7524Mycophenol mofetil oral 5 mg5 MG$0.002J-codeJ7517 (250 MG, ×50 units)
J7526Inj mycophenola mofetil 5 mg5 MG$0.200J-codeJ7519 (10 MG, ×2 units)
J7529Mycop mofetil susp oral 5 mg5 MG$0.034J-codeJ7528 (100 MG, ×20 units)
J7530Mycophenolat (myhibbin) 5 mg5 MG$0.115J-codeJ7514 (100 MG, ×20 units)
J8541Oral, hemady, 0.25 mg0.25 MG$0.375J-code
J9186Inj etoposide (avyxa), 1 mg1 MG$4.240J-code
J9187Inj, etoposide, 1 mg1 MG$0.094J-codeJ9181 (10 MG, ×10 units)
J9191Inj fluorouracil (avyxa)10mg10 MG$14.840J-code
J9192Inj, fluorouracil, 10 mg10 MG$0.039J-codeJ9190 (500 MG, ×50 units)
J9275Inj cosibelimab-ipdl, 2 mg2 MG$21.989J-code
J9318Inj romidepsin non-lyo 0.1mg0.1 MG$32.864J-codeback on the file after a gap
J9361Inj, efbemalenograstim alfa-0.5 MG$121.429J-code
J9362Inj, trabectedin, 0.01 mg0.01 MG$41.844J-codeJ9352 (0.1 MG, ×10 units)
Q0166Granisetron hcl 1 mg oral1 MG$0.774Q-code
Q2058Obecbtge autol up to 400 milPer Therapeutic Dose$293,725.702Q-code
Q5161Inj, denosumab-kyqq, 1 mg1 MG$27.509biosimilar (Q5)
Q5167Inj, denosumab-qbde, 1 mg1 MG$7.681biosimilar (Q5)
Q5168Inj. nufymco, 0.1 mg0.1 MG$26.384biosimilar (Q5)
Q5169Inj, armlupeg, 0.5 mg0.5 MG$519.481biosimilar (Q5)

Retired in Q4 2026

CodeDescriptor (last quarter listed)Billing unitBill instead
J0640Leucovorin calcium injection50 MGJ0643 (1 MG — ×50 units for the same dose) · branded: J0644
J1953Levetiracetam injection10 MGJ1957 (5 MG — ×2 units for the same dose)
J7514Mycophenol (myhibbin) 100 mg100 MGJ7530 (5 MG — ×20 units for the same dose)
J7517Mycophenolate mofetil oral250 MGJ7524 (5 MG — ×50 units for the same dose)
J7519Inj. mycophenolate mofetil10 MGJ7526 (5 MG — ×2 units for the same dose)
J7528Mycophen mofetil for susp100 MGJ7529 (5 MG — ×20 units for the same dose)
J9181Etoposide injection10 MGJ9187 (1 MG — ×10 units for the same dose) · branded: J9186
J9190Fluorouracil injection500 MGJ9192 (10 MG — ×50 units for the same dose) · branded: J9191
J9352Injection trabectedin 0.1mg0.1 MGJ9362 (0.01 MG — ×10 units for the same dose)
J9394Inj, fulvestrant (fresenius)25 MG

Largest payment-limit moves among covered drugs, Q4 2026

CodeDescriptorQ3 2026Q4 2026Change
J9305Inj. pemetrexed nos 10mg$6.952$1.230-82.3%
J9263Oxaliplatin$0.055$0.087+58.2%
J2778Ranibizumab injection$51.090$26.384-48.4%
J9264Paclitaxel protein bound$6.586$3.640-44.7%
J2506Inj pegfilgrast ex bio 0.5mg$143.233$201.241+40.5%
J9041Injection, bortezomib, 0.1mg$2.037$2.628+29.0%
J9060Cisplatin 10 mg injection$2.130$2.497+17.2%
J0875Injection, dalbavancin$11.293$9.439-16.4%
Q2050Doxorubicin inj 10mg$116.605$97.823-16.1%
J9206Irinotecan injection$1.851$1.569-15.2%

Q3 2026

· 11 added, 9 retired

Effective July 1, 2026 · 11 codes added, 9 retired, 818 payment limits changed vs Q2 2026.

Added in Q3 2026

CodeDescriptorBilling unitPayment limitFamilyReplaces
J0681Inj ceftobipole medocarl 3mg3 MG$1.098J-code
J7674Methacholine chloride, neb1 MG$1.942J-codeback on the file after a gap
J9053Inj belantamab mafodot blmf0.1 MG$36.250J-code
J9062Inj amivantamab 5mg hyaluron5 MG$40.743J-code
J9161Inj denileuk difti-cxdl 1mcg1 MCG$12.826J-code
J9174Inj, docetaxel (beizray) 1mg1 MG$46.808J-code
J9232Inj docetaxel (hospira) 1 mg1 MG$0.512J-code
Q0234Inj, tocilizumab-bavi, 1mg1 MG$6.327Q-code
Q0238Inj, tocilizumab-aazg, hospi1 MG$5.581Q-code
Q5098Inj ustekinumab-srlf, 1 mg1 MG$11.551biosimilar (Q5)
Q5160Inj, jobevne, 10 mg10 MG$82.236biosimilar (Q5)

Retired in Q3 2026

CodeDescriptor (last quarter listed)Billing unitBill instead
J0565Inj, bezlotoxumab, 10 mg10 MG
J1748Inj, zymfentra, 10 mg10 MG
J2840Inj, sebelipase alfa, 1 mg1 MG
J3403Revakinagene, per implantPER IMPLANT
J7314Inj., yutiq, 0.01 mg0.01 MG
J9196Inj gemcitabine hcl (accord)200 MG
J9295Injection, necitumumab, 1 mg1 MG
J9296Inj pemetrexed (accord) 10mg10 mg
J9318Inj romidepsin non-lyo 0.1mg0.1 MGre-listed in Q4 2026

Largest payment-limit moves among covered drugs, Q3 2026

CodeDescriptorQ2 2026Q3 2026Change
J9305Inj. pemetrexed nos 10mg$4.038$6.952+72.2%
Q2050Doxorubicin inj 10mg$71.861$116.605+62.3%
Q0138Ferumoxytol, non-esrd$0.229$0.370+61.6%
J0583Bivalirudin$0.124$0.166+33.9%
J9263Oxaliplatin$0.078$0.055-29.5%
J0875Injection, dalbavancin$15.003$11.293-24.7%
J2778Ranibizumab injection$67.853$51.090-24.7%
J9267Paclitaxel injection$0.147$0.112-23.8%
J2267Inj, mirikizumab-mrkz, 1 mg$42.092$32.658-22.4%
J9206Irinotecan injection$1.532$1.851+20.8%

Q2 2026

· 20 added, 11 retired

Effective April 1, 2026 · 20 codes added, 11 retired, 778 payment limits changed vs Q1 2026.

Added in Q2 2026

CodeDescriptorBilling unitPayment limitFamilyReplaces
J0463Inj atropine (fresenius te)0.01 MG$0.014J-code
J0759Inj, clevidipine, 1 mg1 MG$2.844J-code
J1164Inj diltiazem in 0.72% nacl0.5 MG$0.179J-code
J1553Inj yimmugo 100 mg100 MG$24.323J-code
J1612Inj glucagon (gvoke) 0.01 mg0.01 MG$2.365J-code
J2545Pentamidine non-comp unit300 MG$73.565J-codeback on the file after a gap
J8502Inj, aponvie, 1 mg1 MG$1.953J-code
J8515Cabergoline, oral 0.25mg0.25 MG$0.154J-code
J9183Gemcitabine intravesical sys225 MG$73,088.260J-code
J9184Inj gemcitabin (avyxa) 200mg200 MG$410.439J-code
J9277Pembrolizumab 1mg berahyalur1 MG$32.129J-code
J9278Inj, carboplatin (avyxa)1 MG$5.242J-code
J9282Mitomycin intravesical inst1 MG$278.332J-code
J9601Inj linvoseltamab-gcpt 1 mg1 MG$99.502J-code
Q0237Inj, tocilizumab-anoh, hospi1 MG$4.920Q-code
Q5134Inj, tyruko, 1 mg1 MG$24.321biosimilar (Q5)
Q5156Inj, tocilizumab-anoh, 1 mg1 MG$4.635biosimilar (Q5)
Q5157Inj, denosumab-bmwo, 1 mg1 MG$26.209biosimilar (Q5)
Q5158Inj, denosumab-bnht, 1 mg1 MG$29.797biosimilar (Q5)
Q5162Inj, den (bil/bil), bio, 1mg1 MG$15.841biosimilar (Q5)

Retired in Q2 2026

CodeDescriptor (last quarter listed)Billing unitBill instead
90586Bcg vaccine intravesical1 EACH
90759Hep b vac 3ag 10mcg 3 dos im10 MCG
J0841Inj crotalidae im f(ab')2 eq120 MGre-listed in Q4 2026
J0893Inj, decitabine (sun pharma)1 MG
J2313Inj, naloxone (zimhi) 0.01mg0.01 MG
J3471Ovine, up to 999 usp units1 USP UNIT
J7674Methacholine chloride, neb1 MGre-listed in Q3 2026
J8670Rolapitant, oral, 1mg1 MG
J9202Goserelin acetate implant3.6 MG
J9323Inj pemetrexed ditromethamin10 mg
Q4074Iloprost non-comp unit doseUP TO 20 MCG

Largest payment-limit moves among covered drugs, Q2 2026

CodeDescriptorQ1 2026Q2 2026Change
J0883Argatroban nonesrd use 1mg$0.609$1.013+66.3%
J9263Oxaliplatin$0.047$0.078+66.0%
J9267Paclitaxel injection$0.099$0.147+48.5%
Q0138Ferumoxytol, non-esrd$0.360$0.229-36.4%
Q2050Doxorubicin inj 10mg$104.008$71.861-30.9%
J9264Paclitaxel protein bound$8.184$6.020-26.4%
J0878Daptomycin injection$0.028$0.034+21.4%
J0583Bivalirudin$0.157$0.124-21.0%
J9041Injection, bortezomib, 0.1mg$2.678$2.253-15.9%
J0888Epoetin beta non esrd$1.215$1.033-15.0%

Q1 2026

· 21 added, 156 retired

Effective January 1, 2026 · 21 codes added, 156 retired, 778 payment limits changed vs Q4 2025.

Added in Q1 2026

CodeDescriptorBilling unitPayment limitFamilyReplaces
J0162Inj epinephrine (fresenius)0.1 MG$0.455J-code
J0164Epinephrine in nacl (baxter)0.1 MG$0.941J-code
J0458Aztreonam/avibactam 10 mg10 MG$1.678J-code
J1307Inj, crovalimab-akkz, 10 mg10 MG$551.512J-code
J1597Inj glycopyrrolate, glyrx-pf0.1 MG$1.276J-code
J1837Inj, posaconazole, 1 mg1 MG$0.346J-code
J2516Pentamidine non-comp unit1 MG$0.235J-code
J2596Vasopressin (long grove) 1 u1 UNIT$1.790J-code
J3376Inj vancomycin (hikma) 10mg10 MG$0.019J-code
J3379Inj, valproate sod, 5 mg5 MG$0.045J-code
J3403Revakinagene, per implantPER IMPLANT$265,000.000J-code
J7174Injection fitusiran 0.04 mg0.04 MG$132.620J-code
J7514Mycophenol (myhibbin) 100 mg100 MG$2.243J-code
J7528Mycophen mofetil for susp100 MG$0.240J-code
J9256Inj, nipocalimab-aahu, 3 mg3 MG$32.743J-code
J9326Telisotuzumab vedotin-tllv1 MG$145.871J-code
J9341Inj thiotepa (tepylute) 1 mg1 MG$38.550J-code
Q5136Inj. denosumab-bbdz, 1 mg1 MG$28.230biosimilar (Q5)
Q5148Inj, nyposi 1 mcg1 MCG$0.997biosimilar (Q5)
Q5151Inj, eculizumab-aagh, 2 mg2 MG$31.672biosimilar (Q5)
Q5152Inj, eculizumab-aeeb, 2 mg2 MG$42.347biosimilar (Q5)

Retired in Q1 2026

CodeDescriptor (last quarter listed)Billing unitBill instead
90670Pcv13 vaccine im0.5 ML
J0172Inj, aducanumab-avwa, 2 mg2 MG
J0287Amphotericin b lipid complex10 MG
J2545Pentamidine non-comp unit300 MGre-listed in Q2 2026
Q4101Apligraf1 SQ CM
Q4102Oasis wound matrix1 SQ CM
Q4103Oasis burn matrix1 SQ CM
Q4104Integra bmwd1 SQ CM
Q4105Integra drt or omnigraft1 SQ CM
Q4108Integra matrix1 SQ CM
Q4110Primatrix1 SQ CM
Q4111Gammagraft1 SQ CM
Q4114Integra flowable wound matri1 CC
Q4115Alloskin1 SQ CM
Q4118Matristem micromatrix1 MG
Q4121Theraskin1 SQ CM
Q4123Alloskin1 SQ CM
Q4124Oasis tri-layer wound matrix1 SQ CM
Q4126Memoderm/derma/tranz/integup1 SQ CM
Q4127Talymed1 SQ CM
Q4128Flexhd/allopatchhd/sq cm1 SQ CM
Q4132Grafix core, grafixpl core1 SQ CM
Q4133Grafix stravix prime pl sqcm1 SQ CM
Q4137Amnioexcel biodexcel 1sq cm1 SQ CM
Q4138Biodfence dryflex, 1cm1 SQ CM
Q4140Biodfence 1cm1 SQ CM
Q4141Alloskin ac, 1 cm1 SQ CM
Q4143Repriza, 1cm1 SQ CM
Q4145Epifix, inj, 1mg1 MG
Q4148Neox neox rt or clarix cord1 SQ CM
Q4150Allowrap ds or dry 1 sq cm1 SQ CM
Q4151Amnioband, guardian 1 sq cm1 SQ CM
Q4152Dermapure 1 square cm1 SQ CM
Q4153Dermavest, plurivest sq cm1 SQ CM
Q4154Biovance 1 square cm1 SQ CM
Q4155Neoxflo or clarixflo 1 mg1 MG
Q4156Neox 100 or clarix 1001 SQ CM
Q4158Kerecis omega3, per sq cm1 SQ CM
Q4159Affinity1 square cm1 SQ CM
Q4160Nushield 1 square cm1 SQ CM
Q4161Bio-connekt per square cm1 SQ CM
Q4163Woundex, bioskin, per sq cm1 SQ CM
Q4164Helicoll, per square cm1 SQ CM
Q4166Cytal, per square centimeter1 SQ CM
Q4169Artacent wound, per sq cm1 SQ CM
Q4170Cygnus, per sq cm1 SQ CM
Q4171Interfyl, 1 mg1 MG
Q4173Palingen or palingen xplus1 SQ CM
Q4175Miroderm1 SQ CM
Q4178Floweramniopatch, per sq cm1 SQ CM
Q4180Revita, per sq cm1 SQ CM
Q4184Cellesta or duo per sq cm1 SQ CM
Q4186Epifix 1 sq cm1 SQ CM
Q4187Epicord 1 sq cm1 SQ CM
Q4188Amnioarmor 1 sq cm1 SQ CM
Q4190Artacent ac 1 sq cm1 SQ CM
Q4191Restorigin 1 sq cm1 SQ CM
Q4193Coll-e-derm 1 sq cm1 SQ CM
Q4194Novachor 1 sq cm1 SQ CM
Q4195Puraply 1 sq cm1 SQ CM
Q4196Puraply am 1 sq cm1 SQ CM
Q4197Puraply xt 1 sq cm1 SQ CM
Q4199Cygnus matrix, per sq cm1 SQ CM
Q4201Matrion 1 sq cm1 SQ CM
Q4203Derma-gide, 1 sq cm1 SQ CM
Q4204Xwrap 1 sq cm1 SQ CM
Q4205Membrane graft or wrap sq cm1 SQ CM
Q4217Woundfix biowound plus xplus1 SQ CM
Q4221Amniowrap2 per sq cm1 SQ CM
Q4222Progenamatrix, per sq cm1 SQ CM
Q4225Amnio or derma tl, per sq cm1 SQ CM
Q4227Amniocore per sq cm1 SQ CM
Q4229Cogenex amnio memb per sq cm1 SQ CM
Q4232Corplex, per sq cm1 SQ CM
Q4234Xcellerate, per sq cm1 SQ CM
Q4235Amniorepair or altiply sq cm1 SQ CM
Q4236Carepatch per sq cm1 SQ CM
Q4238Derm-maxx, per sq cm1 SQ CM
Q4239Amnio-maxx or lite per sq cm1 SQ CM
Q4248Dermacyte amn mem allo sq cm1 SQ CM
Q4249Amniply, per sq cm1 SQ CM
Q4250Amnioamp-mp per sq cm1 SQ CM
Q4252Vendaje, per square centimet1 SQ CM
Q4253Zenith amniotic membrane psc1 SQ CM
Q4256Mlg complet, per sq cm1 SQ CM
Q4257Relese, per sq cm1 SQ CM
Q4258Enverse, per sq cm1 SQ CM
Q4259Celera per sq cm1 SQ CM
Q4262Dual layer impax, per sq cm1 SQ CM
Q4263Surgraft tl, per sq cm1 SQ CM
Q4264Cocoon membrane, per sq cm1 SQ CM
Q4265Neostim tl per sq cm1 SQ CM
Q4266Neostim per sq cm1 SQ CM
Q4267Neostim dl per sq cm1 SQ CM
Q4268Surgraft ft per sq cm1 SQ CM
Q4269Surgraft xt per sq cm1 SQ CM
Q4270Complete sl per sq cm1 SQ CM
Q4271Complete ft per sq cm1 SQ CM
Q4274Esano ac, per sq cm1 SQ CM
Q4275Esano aca, per sq cm1 SQ CM
Q4276Orion, per sq cm1 SQ CM
Q4278Epieffect, per sq cm1 SQ CM
Q4279Vendaje ac, per sq cm1 SQ CM
Q4280Xcell amnio matrix per sq cm1 SQ CM
Q4281Barrera slor dl per sq cm1 SQ CM
Q4282Cygnus dual per sq cm1 SQ CM
Q4283Biovance tri or 3l, sq cm1 SQ CM
Q4289Revoshield+ amnio, per sq cm1 SQ CM
Q4290Membrane wrap hydr per sq cm1 SQ CM
Q4293Acesso dl, per sq cm1 SQ CM
Q4294Amnio quad-core, per sq cm1 SQ CM
Q4295Amnio tri-core, per sq cm1 SQ CM
Q4296Rebound matrix, per sq cm1 SQ CM
Q4297Emerge matrix, per sq cm1 SQ CM
Q4298Amnicore pro, per sq cm1 SQ CM
Q4299Amnicore pro+, per sq cm1 SQ CM
Q4300Acesso tl, per sq cm1 SQ CM
Q4301Activate matrix, per sq cm1 SQ CM
Q4302Complete aca, per sq cm1 SQ CM
Q4303Complete aa, per sq cm1 SQ CM
Q4304Grafix plus, per sq cm1 SQ CM
Q4309Via matrix, per sq cm1 SQ CM
Q4310Procenta, per 100 mg100 MG
Q4312Acesso ac, per sq cm1 SQ CM
Q4313Dermabind fm, per sq cm1 SQ CM
Q4314Reeva, per sq cm1 SQ CM
Q4316Amchoplast, per sq cm1 SQ CM
Q4317Vitograft, per sq cm1 SQ CM
Q4319Sanograft, per sq cm1 SQ CM
Q4320Pellograft, per sq cm1 SQ CM
Q4321Renograft, per sq cm1 SQ CM
Q4322Caregraft, per sq cm1 SQ CM
Q4323Alloply, per sq cm1 SQ CM
Q4325Acapatch, per sq cm1 SQ CM
Q4326Woundplus, per sq cm1 SQ CM
Q4328Most, per sq cm1 SQ CM
Q4331Axolotl graft, per sq cm1 SQ CM
Q4332Axolotl dualgraft, per sq cm1 SQ CM
Q4339Artacent vericlen, per sq cm1 SQ CM
Q4340Simpligraft, per sq cm1 SQ CM
Q4341Simplimax, per sq cm1 SQ CM
Q4342Theramend, per sq cm1 SQ CM
Q4343Dermacyte ac matrx per sq cm1 SQ CM
Q4344Tri membrane wrap, per sq cm1 SQ CM
Q4345Matrix hd allogrft per sq cm1 SQ CM
Q4346Shelter dm matrix per sq cm1 SQ CM
Q4347Rampart dl matrix per sq cm1 SQ CM
Q4348Sentry sl matrix per sq cm1 SQ CM
Q4350Palisade dm matrix per sq cm1 SQ CM
Q4353Xceed tl matrix per sq cm1 SQ CM
Q4355Abio xpl abio xpl hy p sq cm1 SQ CM
Q4357Xwrap plus, per sq cm1 SQ CM
Q4358Xwrap dual, per sq cm1 SQ CM
Q4359Choriply, per sq cm1 SQ CM
Q4361Epixpress, per sq cm1 SQ CM
Q4367Amniocore sl, per sq cm1 SQ CM

Largest payment-limit moves among covered drugs, Q1 2026

CodeDescriptorQ4 2025Q1 2026Change
J9263Oxaliplatin$0.083$0.047-43.4%
J2506Inj pegfilgrast ex bio 0.5mg$89.344$122.837+37.5%
J9267Paclitaxel injection$0.135$0.099-26.7%
J2919Inj, methylpred sod succ 5mg$0.210$0.264+25.7%
J2778Ranibizumab injection$86.384$65.443-24.2%
J0883Argatroban nonesrd use 1mg$0.796$0.609-23.5%
J9264Paclitaxel protein bound$10.543$8.184-22.4%
J1652Fondaparinux sodium$0.723$0.877+21.3%
J9045Carboplatin injection$2.471$2.929+18.5%
J9305Inj. pemetrexed nos 10mg$4.355$3.594-17.5%

Q4 2025

· 44 added, 2 retired

Effective October 1, 2025 · 44 codes added, 2 retired, 884 payment limits changed vs Q3 2025.

Added in Q4 2025

CodeDescriptorBilling unitPayment limitFamilyReplaces
91323SARSCOV2 VAC 10 MCG/0.2ML IM10 MCG$201.913CPT
J0163Epinephrine in nacl (endo)0.1 MG$0.974J-code
J0462Atropine sulf, nte, 0.01 mg0.01 MG$0.135J-code
J0582Bivalirudin (endo) 1 mg1 MG$0.139J-code
J0614Inj, treosulfan, 50 mg50 MG$32.330J-code
J0738Hiv prep, inj, lenacapavir1 MG$16.133J-code
J0752Hiv prep, oral lenacapavir300 MG$449.030J-code
J0901Vadadustat oral 1mg for esrd1 MG$0.143J-code
J1809Inj, fosdenopterin, 0.1mg0.1 MG$16.971J-code
J2151Inj, mannitol, 250 mg250 MG$0.061J-code
J2291Inj, nafcillin (baxter) 20mg20 MG$0.150J-code
J2428Inj, erzofri, 1 mg1 MG$16.764J-code
J3402Inj. remestemcel-l-rknd/ tdPer Therapeutic Dose$205,640.000J-code
J7173Inj. concizumab-mtci, 0.5 mg0.5 MG$86.405J-code
J7356Inj foscarb/foslevodopa 5 mg0.25 MG - 5 MG$0.706J-code
J9011Datopotamab deruxtecan, 1 mg1 MG$51.558J-code
J9038Inj axatilimab-csfr 0.1 mg0.1 MG$55.650J-code
J9054Inj bortezomib boruzu 0.1 mg0.1 MG$26.150J-code
J9289Inj nivolumab 2 mg hyaluron2 MG$27.362J-code
J9382Inj zenocutuzumab-zbco 1 mg1 MG$32.910J-code
Q4268Surgraft ft per sq cm1 SQ CM$452.707Q-code
Q4269Surgraft xt per sq cm1 SQ CM$1,804.956Q-codeback on the file after a gap
Q4312Acesso ac, per sq cm1 SQ CM$2,411.764Q-code
Q4314Reeva, per sq cm1 SQ CM$2,332.000Q-code
Q4317Vitograft, per sq cm1 SQ CM$4,770.000Q-code
Q4319Sanograft, per sq cm1 SQ CM$2,809.000Q-codeback on the file after a gap
Q4320Pellograft, per sq cm1 SQ CM$103.026Q-code
Q4321Renograft, per sq cm1 SQ CM$3,816.000Q-code
Q4340Simpligraft, per sq cm1 SQ CM$1,377.894Q-code
Q4345Matrix hd allogrft per sq cm1 SQ CM$2,650.000Q-code
Q4346Shelter dm matrix per sq cm1 SQ CM$3,663.787Q-code
Q4347Rampart dl matrix per sq cm1 SQ CM$3,099.433Q-code
Q4348Sentry sl matrix per sq cm1 SQ CM$2,034.877Q-code
Q4350Palisade dm matrix per sq cm1 SQ CM$3,608.093Q-code
Q4353Xceed tl matrix per sq cm1 SQ CM$4,148.840Q-code
Q4355Abio xpl abio xpl hy p sq cm1 SQ CM$2,835.716Q-code
Q4358Xwrap dual, per sq cm1 SQ CM$5,893.344Q-code
Q4359Choriply, per sq cm1 SQ CM$2,779.320Q-code
Q5099Inj ustekinumab-stba, 1 mg1 MG$12.642biosimilar (Q5)
Q5100Inj ustekinumab-kfce, 1 mg1 MG$24.979biosimilar (Q5)
Q5138Inj, wezlana, iv, 1 mg1 MG$11.645biosimilar (Q5)
Q9997Ustekinumab-ttwe iv inj 1 mg1 MG$9.287Q-code
Q9998Inj ustekinumab-aekn, 1 mg1 MG$37.520Q-code
Q9999Inj ustekinumab-aauz 1 mg1 MG$33.088Q-code

Retired in Q4 2025

CodeDescriptor (last quarter listed)Billing unitBill instead
91318SARSCOV2 VAC 3MCG TRS-SUC IM0.3 ML
J2150Mannitol injection50 ML

Largest payment-limit moves among covered drugs, Q4 2025

CodeDescriptorQ3 2025Q4 2025Change
J9041Injection, bortezomib, 0.1mg$1.589$2.791+75.6%
J2506Inj pegfilgrast ex bio 0.5mg$58.399$89.344+53.0%
J9267Paclitaxel injection$0.106$0.135+27.4%
J9206Irinotecan injection$1.397$1.751+25.3%
J2919Inj, methylpred sod succ 5mg$0.259$0.210-18.9%
J9060Cisplatin 10 mg injection$1.948$2.294+17.8%
J9045Carboplatin injection$2.111$2.471+17.1%
J9305Inj. pemetrexed nos 10mg$3.734$4.355+16.6%
J1437Inj. fe derisomaltose 10 mg$18.951$22.018+16.2%
J9264Paclitaxel protein bound$12.122$10.543-13.0%

Q3 2025

· 40 added, 12 retired

Effective July 1, 2025 · 40 codes added, 12 retired, 856 payment limits changed vs Q2 2025.

Added in Q3 2025

CodeDescriptorBilling unitPayment limitFamilyReplaces
J0165Inj epinephrine nos 0.1 mg0.1 MG$0.580J-code
J0166Inj epinephrine (bpi)0.1 MG$2.282J-code
J0167Inj epinephrine (hospira)0.1 MG$0.737J-code
J0168Epinephrine (intl med sys)0.1 MG$2.176J-code
J0169Inj epinephrine (adrenalin)0.1 MG$1.320J-code
J0616Inj metoprolol tartrate 1 mg1 MG$0.134J-code
J1072Inj, testosterone, azmiro1 MG$1.325J-code
J1163Inj, diltiazem hcl, 0.5 mg0.5 MG$0.037J-code
J1326Inj, zolbetuximab-clzb, 2 mg2 MG$33.557J-code
J1749Inj, iloprost, 0.1 mcg0.1 MCG$5.713J-code
J2290Inj, nafcillin sodium, 20 mg20 MG$0.057J-code
J2312Inj naloxone hcl nos, 0.01mg0.01 MG$0.068J-code
J2313Inj, naloxone (zimhi) 0.01mg0.01 MG$0.015J-code
J3373Inj, vancomycin hcl, 10 mg10 MG$0.031J-code
J3374Inj, vancomycin (mylan) 10mg10 MG$0.121J-code
J3375Inj vancomycin (xellia) 10mg10 MG$0.134J-code
J7172Inj marstacim-hncq, 0.5 mg0.5 MG$50.714J-code
J8611Oral methotrexate (jylamvo)2.5 MG$18.528J-code
J8612Oral methotrexate (xatmep)2.5 MG$22.659J-code
J9076Inj, cyclophos (baxter) 5mg5 MG$5.028J-code
J9276Inj zanidatamab-hrii, 2 mg2 MG$25.080J-code
J9292Inj, pemetrexed dipotassium10 MG$83.284J-code
J9318Inj romidepsin non-lyo 0.1mg0.1 MG$28.517J-code
J9329Inj, tislelizumab-jsgr1 MG$57.416J-code
J9342Inj thiotepa nos 1 mg1 MG$12.236J-code
Q2057Afamitresgene autoleucelPER THERAPEUTIC DOSE$770,620.000Q-code
Q4145Epifix, inj, 1mg1 MG$19.478Q-code
Q4169Artacent wound, per sq cm1 SQ CM$2,220.572Q-code
Q4249Amniply, per sq cm1 SQ CM$1,789.545Q-code
Q4316Amchoplast, per sq cm1 SQ CM$4,415.969Q-code
Q4326Woundplus, per sq cm1 SQ CM$1,082.950Q-code
Q4331Axolotl graft, per sq cm1 SQ CM$1,637.549Q-code
Q4339Artacent vericlen, per sq cm1 SQ CM$2,055.340Q-code
Q4341Simplimax, per sq cm1 SQ CM$3,071.281Q-code
Q4342Theramend, per sq cm1 SQ CM$2,127.108Q-code
Q4344Tri membrane wrap, per sq cm1 SQ CM$2,689.477Q-code
Q4357Xwrap plus, per sq cm1 SQ CM$4,770.000Q-code
Q4361Epixpress, per sq cm1 SQ CM$1,590.000Q-code
Q4367Amniocore sl, per sq cm1 SQ CM$530.000Q-code
Q5146Inj, hercessi, 10 mg10 MG$76.181biosimilar (Q5)

Retired in Q3 2025

CodeDescriptor (last quarter listed)Billing unitBill instead
J0171Adrenalin epinephrine inject0.1 MG
J0173Inj, epinephrine (belcher)0.1 MG
J1744Icatibant injection1 MG
J2310Inj naloxone hydrochloride1 MG
J2311Inj, naloxone hcl (zimhi)1 MG
J3370Vancomycin hcl injection500 MG
J3371Inj, vancomycin hcl (mylan)500 MG
J3372Inj, vancomycin hcl (xellia)500 MG
J9340Thiotepa injection15 MG
Q4231Corplex p, per cc1 CC
Q4269Surgraft xt per sq cm1 SQ CMre-listed in Q4 2025
Q4319Sanograft, per sq cm1 SQ CMre-listed in Q4 2025

Largest payment-limit moves among covered drugs, Q3 2025

CodeDescriptorQ2 2025Q3 2025Change
J2506Inj pegfilgrast ex bio 0.5mg$19.981$58.399+192.3%
J9263Oxaliplatin$0.049$0.091+85.7%
Q5128Inj, cimerli, 0.1 mg$146.761$86.513-41.1%
J9041Injection, bortezomib, 0.1mg$2.498$1.589-36.4%
J9060Cisplatin 10 mg injection$2.860$1.948-31.9%
J9045Carboplatin injection$2.930$2.111-28.0%
Q2050Doxorubicin inj 10mg$150.409$109.284-27.3%
J0883Argatroban nonesrd use 1mg$0.950$0.739-22.2%
J1652Fondaparinux sodium$0.855$0.719-15.9%
J9267Paclitaxel injection$0.126$0.106-15.9%

Q2 2025

· 72 added, 6 retired

Effective April 1, 2025 · 72 codes added, 6 retired, 793 payment limits changed vs Q1 2025.

Added in Q2 2025

CodeDescriptorBilling unitPayment limitFamilyReplaces
J0138Inj acetaminoph 10mg/ibu 3mg10 MG/3MG$0.218J-code
J0281Inj aminocaproic acid 1 gram1 GM$1.303J-code
J0287Amphotericin b lipid complex10 MG$10.299J-code
J0589Inj daxibotulinumtoxina-lanm1 UNIT$2.992J-code
J0593Inj., lanadelumab-flyo, 1 mg1 mg$84.802J-code
J0870Injection, imetelstat, 1 mg1 MG$55.510J-code
J0883Argatroban nonesrd use 1mg1 MG$0.950J-code
J0893Inj, decitabine (sun pharma)1 MG$0.777J-code
J0898Argatroban nonesrd (auromed)1 MG$1.338J-code
J0899Argatroban dialysis, auromed1 MG$1.338J-code
J1271Inj doxycycline hyclate 1 mg1 MG$0.120J-code
J1299Inj, eculizumab, 2 mg2 MG$44.809J-code
J1308Inj, famotidine, 0.25 mg0.25 MG$0.008J-code
J1434Inj, focinvez, 1mg1 MG$3.021J-code
J1744Icatibant injection1 MG$125.317J-code
J1790Droperidol injectionup to 5 MG$8.565J-code
J1808Inj, folic acid, 0.1 mg0.1 MG$0.063J-code
J1938Inj, furosemide, 1 mg1 MG$0.020J-code
J2246Inj, micafungin (baxter)1 MG$0.638J-code
J2351Inj ocrelizumab 1mg hya-ocsq1 MG$45.187J-code
J2371Inj phenylephrine hcl 20 mcg20 MCG$0.002J-code
J2468Inj, palonosetron (posfrea)25 MCG$59.905J-code
J2502Inj, pasireotide long acting1 MG$526.942J-code
J2804Inj, rifampin, 1 mg1 MG$0.142J-code
J2865Inj sulfameth/trim 5 mg/1 mg5MG-1MG$0.056J-code
J3300Triamcinolone a inj prs-free1 MG$24.516J-code
J3316Inj., triptorelin xr 3.75 mg3.75 MG$3,506.041J-code
J3471Ovine, up to 999 usp units1 USP UNIT$0.499J-code
J7355Inj travoprost intra impl1 MCG$194.411J-code
J7521Tacrolim granules oral susp0.1 MG$1.334J-code
J7601Ensifentrine inh 3 mg3 MG$52.117J-code
J9024Inj atezolizumb 5mg hya-tqjs5 MG$30.876J-code
J9026Inj, tarlatamab-dlle, 1 mg1 MG$1,570.765J-code
J9072Inj cyclophos avyxa 5mg5 MG$9.053J-code
J9296Inj pemetrexed (accord) 10mg10 mg$9.736J-code
J9323Inj pemetrexed ditromethamin10 mg$10.343J-code
Q4123Alloskin1 SQ CM$71.550Q-code
Q4143Repriza, 1cm1 SQ CM$33.920Q-code
Q4161Bio-connekt per square cm1 SQ CM$1,853.655Q-code
Q4164Helicoll, per square cm1 SQ CM$322.151Q-code
Q4170Cygnus, per sq cm1 SQ CM$444.740Q-code
Q4173Palingen or palingen xplus1 SQ CM$360.508Q-code
Q4180Revita, per sq cm1 SQ CM$1,030.144Q-code
Q4193Coll-e-derm 1 sq cm1 SQ CM$1,608.269Q-code
Q4204Xwrap 1 sq cm1 SQ CM$2,929.017Q-code
Q4221Amniowrap2 per sq cm1 SQ CM$2,014.000Q-code
Q4227Amniocore per sq cm1 SQ CM$1,192.500Q-code
Q4239Amnio-maxx or lite per sq cm1 SQ CM$2,349.924Q-code
Q4248Dermacyte amn mem allo sq cm1 SQ CM$2,797.108Q-code
Q4250Amnioamp-mp per sq cm1 SQ CM$2,863.134Q-code
Q4263Surgraft tl, per sq cm1 SQ CM$1,712.999Q-code
Q4264Cocoon membrane, per sq cm1 SQ CM$478.060Q-code
Q4269Surgraft xt per sq cm1 SQ CM$2,862.000Q-code
Q4270Complete sl per sq cm1 SQ CM$3,370.800Q-code
Q4274Esano ac, per sq cm1 SQ CM$1,838.291Q-code
Q4275Esano aca, per sq cm1 SQ CM$2,676.500Q-code
Q4290Membrane wrap hydr per sq cm1 SQ CM$1,841.001Q-code
Q4293Acesso dl, per sq cm1 SQ CM$1,584.700Q-code
Q4294Amnio quad-core, per sq cm1 SQ CM$2,650.000Q-code
Q4295Amnio tri-core, per sq cm1 SQ CM$2,332.000Q-code
Q4296Rebound matrix, per sq cm1 SQ CM$1,476.130Q-code
Q4299Amnicore pro+, per sq cm1 SQ CM$2,597.000Q-code
Q4309Via matrix, per sq cm1 SQ CM$1,323.965Q-code
Q4313Dermabind fm, per sq cm1 SQ CM$3,337.231Q-code
Q4319Sanograft, per sq cm1 SQ CM$2,650.000Q-code
Q4322Caregraft, per sq cm1 SQ CM$1,855.000Q-code
Q4323Alloply, per sq cm1 SQ CM$1,643.000Q-code
Q4325Acapatch, per sq cm1 SQ CM$2,067.000Q-code
Q4328Most, per sq cm1 SQ CM$3,710.000Q-code
Q4332Axolotl dualgraft, per sq cm1 SQ CM$1,696.165Q-code
Q4343Dermacyte ac matrx per sq cm1 SQ CM$2,952.100Q-code
Q5147Inj, aflibercept-ayyh, 1 mg1 MG$795.861biosimilar (Q5)

Retired in Q2 2025

CodeDescriptor (last quarter listed)Billing unitBill instead
J0630Calcitonin salmon injection400 UNITS
J1300Eculizumab injection10 MG
J1940Furosemide injection20 MG
J3357Ustekinumab sub cu inj, 1 mg1 MG
J9218Leuprolide acetate injection1 MG
Q3027Inj beta interferon im 1 mcg1 MCG

Largest payment-limit moves among covered drugs, Q2 2025

CodeDescriptorQ1 2025Q2 2025Change
J9263Oxaliplatin$0.075$0.049-34.7%
J9305Inj. pemetrexed nos 10mg$5.272$3.771-28.5%
J1652Fondaparinux sodium$0.672$0.855+27.2%
J2778Ranibizumab injection$123.979$90.414-27.1%
J2354Octreotide inj, non-depot$0.805$0.590-26.7%
J9045Carboplatin injection$3.630$2.930-19.3%
J9206Irinotecan injection$1.974$1.640-16.9%
J9267Paclitaxel injection$0.109$0.126+15.6%
Q5128Inj, cimerli, 0.1 mg$168.744$146.761-13.0%
Q0138Ferumoxytol, non-esrd$0.377$0.328-13.0%

Get the next quarter's list by email

The Quarterly Rate Reset carries exactly this diff — every new and retired code with its descriptor and payment limit, plus the largest moves — the day the new quarter's file is loaded. No filler between quarters.

Frequently asked

A drug I bill just got a new J-code. When do I switch?
On the effective date of the quarter the code appears in (the first day of that quarter). Claims for dates of service before it keep the old code, usually the unclassified J3490/J3590/C9399 with the NDC. Most payers reject the new code on earlier dates and the old code on later ones.
What is a Q5 code?
A biosimilar. CMS assigns each biosimilar its own Q5xxx code so it can be paid at its own ASP rather than the reference product's. The reference product keeps its J-code. When a biosimilar launches, its Q5 code appears here in the quarter it was added to the file.
A code disappeared from the file. Is the drug no longer covered?
Not necessarily. A code is retired when the product is discontinued, when CMS consolidates it into another code, or when the manufacturer stops reporting ASP and the drug moves to a different pricing method. Check the retired table for the last descriptor, then the drug page for its current code.
Where does this list come from?
From the quarterly Medicare Part B payment-limit file published by CMS, loaded into this site's data each quarter. The diff between consecutive quarters is computed at build time; nothing on this page is typed by hand.

Related references

Price the new code at your payer

CareCost carries every code in the current file with its payment limit and your payer’s published rate, so a code that appeared this quarter prices the day it is loaded.

Run a free estimate

Sources & how this is maintained

Source
CMS Medicare Part B Payment Limit Files, 2025 Q1 through Q4 2026. Loaded per docs/medicare-asp-refresh.md; the ingested quarter is recorded in data/ingested-quarters.json.
Computed
Added = in this quarter's file and not the previous; retired = the reverse; moves = payment-limit change on the same code. Ten largest moves shown per quarter.
What this page does not know
Why a code was retired, or a code's coverage status. Descriptors are CMS's short descriptors.
Corrections
Send one with the code and quarter.