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Keytruda copay assistance programs

With commercial insurance: Merck Co-pay Assistance Program for KEYTRUDA Injection 100 mg or KEYTRUDA QLEX — as little as $25 per dose, up to $25,000 a year. With Medicare: the Keytruda card can’t be used. 2 foundation funds are open today (as of October 12, 2026). See them by diagnosis below.

Copay program checked September 28, 2026 · Source ↗

See what this patient owes after assistance →

14 assistance programs for Keytruda patients · 4 open today

Manufacturer savings, charitable foundations, and patient assistance programs.

Select the patient's insurance and diagnosis to see which programs apply.

Current status · Award amounts · Eligibility · Direct application links

Keytruda assistance, in the order you will use it

Copay program · Merck Co-pay Assistance Program for KEYTRUDA (pembrolizumab) Injection 100 mg or KEYTRUDA QLEX

Open
Who qualifiesCommercial/private insurance only; US or Puerto Rico residents; excludes Medicaid, Medicare (incl Part D/Advantage), TRICARE, CHAMPUS, PR Government Health Insurance Plan, other state/federal programs
What it pays forThe Keytruda card pays for the drug only, not the infusion or injection fee.
Yearly max$25,000 per patient per 12-month eligibility period
Per claimPatient pays first $25 of co-pay per administration; program pays the rest up to the annual max
Clinic-billed (medical benefit) claimsYes. Submitted by: the provider or the patient. Claim deadline: 180 days from the date the claim was processed (hub page also mentions a 90-day lookback for prior treatments).
How to submitInsurer EOB/Remittance Advice showing patient out-of-pocket cost, confirmation of administration and date; enrollment form by fax or electronic; hub fax 855-755-0518.
Phone855-257-3932

Checked September 28, 2026 · Source 1 ↗ · Source 2 ↗

Free-drug program · Merck Patient Assistance Program

Open
Who qualifiesIncome: Individual $79,800 or less; couple $108,200 or less; family of 4 $165,000 or less annually (AK/HI call 1-800-727-5400). Insurance: Must not have insurance or other coverage for the medication, including private, Medicaid, Medicare; exception: may qualify if attesting special circumstances of financial and medical hardship and income meets criteria.
Phone855-257-3932

Checked September 28, 2026 · Source ↗

If the patient has Medicare

Keytruda’s card can’t be used with Medicare. These funds may help. They open and close with donations, so call before telling a Keytruda patient no.

HealthWell Foundation – Renal Cell Carcinoma - Medicare AccessOpen $8,000 lists Keytruda
Checked October 12, 2026 · Source ↗
HealthWell Foundation – Chronic Lymphocytic Leukemia (page lists Keytruda; not a Keytruda indication)Open $8,000 lists Keytruda
Checked October 12, 2026 · Source ↗
HealthWell Foundation – Non-Small Cell Lung Cancer - Medicare AccessClosed $6,000 lists Keytruda
Checked September 29, 2026 · Source ↗
HealthWell Foundation – Melanoma - Medicare AccessClosed $6,500 lists Keytruda
Checked October 12, 2026 · Source ↗
HealthWell Foundation – Bladder and Urothelial Cancer - Medicare AccessClosed $5,000 lists Keytruda
Checked October 12, 2026 · Source ↗
HealthWell Foundation – Head and Neck Cancer - Medicare AccessClosed $6,500 lists Keytruda
Checked October 12, 2026 · Source ↗
HealthWell Foundation – Breast Cancer - Medicare AccessClosed $7,500 lists Keytruda
Checked October 12, 2026 · Source ↗
HealthWell Foundation – Gastric Cancer - Medicare AccessClosed $8,500 lists Keytruda
Checked October 12, 2026 · Source ↗
HealthWell Foundation – Hepatocellular Carcinoma - Medicare AccessClosed $6,500 lists Keytruda
Checked October 12, 2026 · Source ↗
HealthWell Foundation – Colorectal Carcinoma - Medicare AccessClosed $8,000 lists Keytruda
Checked October 12, 2026 · Source ↗
HealthWell Foundation – Small Cell Lung Cancer - Medicare AccessClosed $8,000 lists Keytruda
Checked October 12, 2026 · Source ↗
HealthWell Foundation – Pancreatic Cancer - Medicare AccessClosed $6,000 lists Keytruda
Checked October 12, 2026 · Source ↗

Support hub · Merck Access Program

What they doBenefit verification, prior authorization support, assistance with copay and patient assistance programs; fax 855-755-0518
Phone855-257-3932

Checked September 28, 2026 · Source 1 ↗ · Source 2 ↗

1 program matches this patient · 1 open · 1 more if coverage falls short

Keytruda · Non-small cell lung cancer · Commercial insurance

Merck Co-pay Assistance Program for KEYTRUDA (pembrolizumab) Injection 100 mg or KEYTRUDA QLEXOpen

Eligible patients may pay $25 per dose

Potential benefit$25/dose · $25,000/year annual maximum applies
InsuranceCommercial ✓ · Government insurance ✗
DiagnosisNon-small cell lung cancer ✓
IncomeNo income requirement
Covers administrationNo — the infusion fee is not covered
Phone855-257-3932
Current statusOpen
Last verifiedSeptember 28, 2026

Calculate this patient’s cost with this program ↓

Calculate this patient’s cost with Merck Co-pay Assistance Program for KEYTRUDA (pembrolizumab) Injection 100 mg or KEYTRUDA QLEX

Assistance

Free · No credit card · No sales call

Run the estimate with assistance, without assistance, or both side by side.

What CareCost shows

Example · Keytruda · 200 mg · 200 units · commercial plan · deductible met · 20% coinsurance · allowed amounts at the Medicare reference rate

Without assistanceWith Merck Co-pay Assistance Program for KEYTRUDA (pembrolizumab) Injection 100 mg or KEYTRUDA QLEX
Drug responsibility$2,490.12$25.00
Administration (96413)$26.65$26.65
Patient owes$2,516.77$51.65

Estimated patient savings: $2,465.12

CareCost calculates the drug and administration lines using the patient’s payer rate and benefits; this example uses the Medicare rate as a reference.

1 more Keytruda program for this patient

Also available if this patient’s coverage falls short

Merck Patient Assistance ProgramIf underinsured

Free Merck Patient Assistance Program for eligible patients

Potential benefitFree drug — enrollment period applies
InsuranceUninsured ✓ · Commercial ✗ · Medicare ✗ · Medicaid ✗
DiagnosisNon-small cell lung cancer ✓
IncomeNo insurance or other coverage (private insurance, HMOs, Medicaid and Medicare all count as coverage). A hardship exception may apply if income meets criteria. Income of $79,800 or less (individual), $108,200 (couple) or $165,000 (family of 4). US resident.
Covers administrationNo — the infusion fee is not covered
Phone855-257-3932
Current statusOpen
Last verifiedSeptember 28, 2026

Calculate this patient’s cost with this program ↓

Other Keytruda assistance programs

Change the diagnosis to see only the programs that apply to your patient.

Melanoma6 programsCheck current programs →
Head and neck cancer2 programsCheck current programs →
Hodgkin lymphoma4 programsCheck current programs →
Bladder cancer4 programsCheck current programs →
Gastric or GEJ cancer4 programsCheck current programs →
Esophageal cancer2 programsCheck current programs →
Cervical cancer3 programsCheck current programs →
Renal cell carcinoma4 programsCheck current programs →
Triple-negative breast cancer7 programsCheck current programs →
Colorectal cancer (MSI-H)5 programsCheck current programs →
Hepatocellular carcinoma6 programsCheck current programs →
Endometrial cancer2 programsCheck current programs →
Bone Metastases, Cancer Home Care Services and 10 more12 funds · 3 open

One assistance search. One patient estimate.

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Open the official application✓
Calculate cost before assistance✓
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Calculate what the patient still owes✓

How Keytruda assistance works

Commercial insurance — The Merck Co-pay Assistance Program covers eligible commercially insured patients. It caps the patient's cost at $25 for each KEYTRUDA or KEYTRUDA QLEX administration, up to $25,000 per patient per 12-month Eligibility Period, and does not cover the infusion or office-visit charge. View current program ↑

Medicare — Manufacturer copay savings cannot be used when government insurance is paying for Keytruda; the federal Anti-Kickback Statute is why, per HHS OIG guidance on copayment coupons. Diagnosis-specific charitable foundations cover copays or coinsurance when a fund is accepting applications; the Keytruda-eligible funds -- TotalAssist's NSCLC and RCC funds, HealthWell's RCC fund -- accept only Medicare, Medicaid, or TRICARE patients (check each fund's current status on the funds list). uninsured patients, some commercially insured patients who meet the program's rules and some Medicare patients who meet the program's rules who meet the income limit qualify for free drug through the Merck Patient Assistance Program. View current Medicare funds ↑

Why fund status matters — Foundation funds change between: Open accepting applications now · Waitlist not enrolling immediately · Closed not accepting new applications. Every CareCost program card shows the status and the date it was verified.

Why diagnosis matters — Oncology assistance funds are organized by cancer type, not by the drug alone. Two patients receiving Keytruda for different diagnoses -- non-small cell lung cancer versus renal cell carcinoma, for example -- qualify for different funds, because foundations fund specific cancers, not specific drugs.

Frequently asked questions

Is there a Keytruda copay card?

Yes. Eligible commercially insured patients enrolled in the Merck Co-pay Assistance Program pay the first $25 of each KEYTRUDA or KEYTRUDA QLEX administration, up to $25,000 per patient per 12-month Eligibility Period. It does not cover the infusion or office-visit charge. Apply on the Merck Access Program ↗ Calculate cost with the program →

Can Medicare patients use the Keytruda copay card?

No. The Merck Co-pay Assistance Program is not valid for Medicare, Medicaid, TRICARE, VA, or other government insurance. Uninsured patients may qualify for free drug through the Merck Patient Assistance Program, and Medicare patients may qualify for an independent charitable fund when one is open for their diagnosis. Check current Medicare funds ↑

Are there currently open foundation funds for non-small cell lung cancer?

TotalAssist's Non-Small Cell Lung Cancer fund is limited to Medicare, Medicaid, and TRICARE patients -- it does not accept commercial insurance (check each fund's current status on the funds list). Fund availability changes as foundations receive and exhaust funding. Check today's status ↑

Sources

Data current: programs verified Oct 12, 2026

The Merck Access Program (Co-pay Assistance Program and Patient Assistance Program for KEYTRUDA/KEYTRUDA QLEX) · TotalAssist (Patient Advocate Foundation) · HealthWell Foundation · The Assistance Fund · Good Days · CancerCare · PAN Foundation · Blood Cancer United. Every program links directly to its official source or application page.

Last program check: .

Reviewed September 9, 2026 by Erin Rose, CareCost Estimate founder. Methodology →