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Venofer (J1756) cost and reimbursement per dose

Original Medicare: the patient owes $16.63 for a 200 mg dose

Medicare allows $83.14 for the drug and its administration. The patient owes 20% of it once the Part B deductible is met, and a Medigap plan can take that to $0.

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What sets the amount

Administration (96374) is $37.74 against $45.40 for the drug on the default 200 mg dose — 45% of the $83.14 allowed amount. On most drugs in this reference the drug dominates the claim; here, an unbilled or downcoded administration line costs the practice almost as much as the drug line, and the office-visit code (99214, $135.61) is bigger than the drug itself if it is separately documented.

Medicare allows
$0.227
per unit · ASP+6%, Q3 2026
Part B deductible
$283
in 2026, before the 20% starts
Medigap
$0 with Plans A–G, M, N
Plan K owes $8.31 · Plan L owes $4.16
Commercial
$0.23/mg median (Aetna)
37 payer price files on file
Data current: pricing Q3 2026 · commercial price files Q2 2026 · Part B deductible 2026

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Pick the dose and setting, choose the plan, and add a Medigap plan if there is one.

200 mg (NDD-CKD) and 100 mg (HDD-CKD) both use the 96374 IV push code · pediatric dosing is weight-based, capped at 100 mg per dose

Administration

Venofer has no second administration code on this estimator — 96415 (each additional hour) does not apply to a slow IV push. The 300–400 mg PDD-CKD doses are infused rather than pushed and bill 96365/96366 instead; see the reference table below.

Include only when a significant, separately identifiable E/M service is performed and documented (modifier 25).

ItemQtyPayer allowsPatient owes
Venofer (iron sucrose) J1756200$45.40$9.08
Intravenous push, single drug 963741$37.74$7.55
Total$83.14$16.63
The payer-allows column is what the practice is reimbursed for this claim. The patient-owes column is that patient’s share of it.

Aetna pays its contracted rate ($0.23 per unit, median). What this patient owes depends on their deductible, coinsurance and out-of-pocket position, and on any assistance program.

Medicare's 80% payment is reduced by the 2% sequester; the patient's 20% coinsurance is not affected.

Patient owes
$16.63
20% coinsurance, deductible met

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The estimate above assumes the deductible is already met. Most patients are part-way through theirs for most of the year, and that changes what they owe today.

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What CareCost returns

Original Medicare · Venofer · 200 mg

$16.63

Patient owes · deductible met

Drug responsibility$9.08
Administration + visit$7.55
With assistanceNo open fund for this diagnosis on Medicare today

Commercial estimates use the payer’s published rate and this patient’s actual benefits.


Venofer cost reference

How Medicare pays for Venofer

$0.227 per mg is Part B's ASP+6% rate for Q3 2026. Medicare pays J1756 per 1 mg billing unit, not per vial or per dose — a 10 mg-per-unit drug needs a conversion step first; this one doesn't, units equal the ordered mg directly. On the default 200 mg dose that is $45.40 for the drug, and the administration line (96374, $37.74) is 45% of the $83.14 allowed amount — nearly as large as the drug itself. Full administration code reference: IV push codes 96374–96376 → and IV infusion codes 96365–96366 →. Full explanation: How Medicare Part B drug cost sharing works →

Common Venofer doses and Medicare's allowed amount

DoseUnitsMedicare drug allowed
100 mg100$22.70
200 mg200$45.40
300 mg300$68.10
400 mg400$90.80

What a full 1,000 mg course costs

Every Venofer regimen runs to a 1,000 mg cumulative course, not an open-ended schedule. The NDD-CKD course — 200 mg on 5 different days — is 5 separate claims, each with its own 96374 administration line:

Cost of the full 1,000 mg NDD-CKD course: 5 visits of 200 mg plus 96374 administration.
VisitsDose allowed (5 × $45.40)Administration allowed (5 × $37.74)Course total allowed
5$227.00$188.70$415.70

Administration is 45% of the course total, the same share it is on a single visit — it does not shrink as a proportion of the bill as the course runs. A denied or downcoded 96374 line on any one of the five visits loses the practice nearly as much as a pricing error on the drug line itself.

The ESRD PPS rule: why the estimator defaults to 200 mg

Since January 1, 2011, the Medicare End-Stage Renal Disease Prospective Payment System has paid the dialysis facility one bundled per-treatment rate that covers renal-related items, including IV iron. The 100 mg hemodialysis dose is the commonest clinical use of Venofer, and it is the one setting where the drug is usually not separately billable to Part B:

SettingSeparately payable to Part B?
HDD-CKD, in-center hemodialysis, dose given during dialysisNo — bundled in the ESRD PPS
HDD-CKD, home hemodialysis, administered by the dialysis vendorNo — bundled
NDD-CKD, physician office (POS 11)Yes
PDD-CKD, scheduled infusion at office or HOPD (POS 11/22)Yes
Non-CKD iron-deficiency anemia (off-label), any settingYes, with prior authorization

Because the commonest use of this drug cannot be billed to Part B at all, the estimator above defaults to the 200 mg NDD-CKD dose rather than the 100 mg HDD-CKD dose — that is the regimen a practice can legitimately price against Part B. Confirm the dialysis setting before submitting any J1756 claim.

What each Medigap plan leaves the patient with

For a 200 mg dose (200 units) with the 96374 IV push code, Medicare allows $83.14, and the Part B coinsurance on that is $16.63. Plans A, B, C, D, F, G, M and N cover that coinsurance in full, so those patients owe nothing per dose once the $283 deductible is met; Plan K leaves $8.31 and Plan L $4.16. Those are small numbers, and on this drug they are the wrong ones to look at.

The whole claim is smaller than the deductible. At $83.14 against $283, a patient who has not yet met their Part B deductible for the year pays the entire claim — and does so on eight of the ten plans, because only C and F cover the Part B deductible, and both are closed to anyone newly eligible after 2020. Across the five-visit, 1,000 mg course the first three visits cost the full $83.14, the fourth costs $43.49 and only the fifth costs the $16.63 this table is built on. The patient pays $309.54 for the course, of which $283 is deductible and $26.54 is coinsurance.

That inverts what Medigap is worth here. On a drug where one claim runs to thousands, a plan that covers the coinsurance is the difference between a large bill and none. On Venofer the coinsurance is $26.54 across an entire course, so the plan letter barely matters and the deductible decides almost everything — which is also why the month of the year a course starts changes the bill more than the plan does. See what each Medigap plan (A–N) owes on this claim →

Plan Covers Part B deductible ($283) Covers Part B coinsurance Patient owes, deductible met Patient owes, deductible not met
Plan KNo50%$8.31$83.14
Plan LNo75%$4.16$83.14

Only the letters that leave this patient a balance are listed. The full A–N grid, the high-deductible variants, Plan N’s office-visit carve-out and the MACRA restriction on Plans C and F are at Medigap Plans A–N.

Commercial plans

Commercial payers negotiate their own rate for J1756, not ASP+6% — Aetna's median published rate is about $0.23 per mg, close to Medicare's $0.227, putting a 200 mg dose at about $46.00 before benefits. Full explanation: How commercial drug reimbursement works →

The IV iron class: a 12x spread for the same 1,000 mg

Normalized to 1,000 mg of elemental iron, Q3 2026 ASP+6%:

Medicare Part B allowed amount per 1,000 mg of elemental iron, across six IV iron products.
ProductCodePer unitPer 1,000 mg
Ferrlecit (sodium ferric gluconate)J2916$2.197 / 12.5 mg$175.76
Venofer (iron sucrose)J1756$0.227 / mg$227.00
Feraheme (ferumoxytol), non-ESRDQ0138$0.370 / mg$377.40
INFeD (iron dextran)J1750$18.993 / 50 mg$379.86
Injectafer (ferric carboxymaltose)J1439$1.132 / mg$1,132.00
Monoferric (ferric derisomaltose)J1437$21.077 / 10 mg$2,107.70

A 12x spread separates the cheapest and most expensive products in this class for the same 1,000 mg of iron. Labeled courses differ in the number of visits — Injectafer is dosed 750 mg twice, Feraheme 510 mg twice (a 1,020 mg course), Monoferric a single 1,000 mg dose — so the number of administration claims differs too, which is exactly why the cheapest per-mg product is not automatically the cheapest course. This table compares Medicare allowed amounts only; it is not a clinical recommendation, and no product here is more or less clinically appropriate than another based on price alone.

ASP+6% by quarter

QuarterASP+6% per mg
2025 Q1$0.226
2025 Q2$0.237
2025 Q3$0.224
2025 Q4$0.229
2026 Q1$0.236
2026 Q2$0.223
2026 Q3 (current)$0.227

Patient assistance

American Regent runs one program for Venofer: AR Assist, a free-drug program for patients who are uninsured or have a coverage gap. There is no manufacturer copay card for commercially insured patients and no diagnosis-matched foundation fund open today. Full assistance program details →

ICD-10 codes

D63.1 (Anemia in chronic kidney disease) is the load-bearing diagnosis code — payer policies want it as primary or secondary, and a CKD stage code alone triggers denial. Stage and dialysis-status codes pair with it: N18.4 (CKD stage 4), N18.5 (CKD stage 5), N18.6 (end stage renal disease), and Z99.2 (dependence on renal dialysis, pairing with N18.6). Off-label, non-CKD iron-deficiency anemia bills D50.0, D50.8 or D50.9.

N18.3 is not a billable code. CKD stage 3 bills as N18.30 (unspecified), N18.31 (stage 3a) or N18.32 (stage 3b).

Frequently asked questions

How much does Medicare pay for Venofer?

$0.227 per mg for Q3 2026 (ASP+6%). The standard 200 mg NDD-CKD dose needs 200 units, so Medicare's allowed drug amount is $45.40.

What does a Venofer dose cost a Medicare patient?

For a 200 mg dose with the 96374 IV push administration code, Medicare allows $83.14 and the patient's 20% coinsurance is $16.63 after the Part B deductible is met. What each Medigap plan leaves on this claim ↓

Why is administration such a large share of the Venofer bill?

Administration (96374) is $37.74 against $45.40 for the drug — 45% of the $83.14 allowed amount. On most drugs in this reference the drug dominates the claim; here, an unbilled or downcoded administration line costs the practice almost as much as the drug line itself.

Can Venofer given during hemodialysis be billed to Medicare Part B?

Usually not. Under the ESRD Prospective Payment System, iron sucrose given during in-center or home hemodialysis is bundled into the dialysis facility's per-treatment rate and is not separately payable to Part B. A non-dialysis (NDD-CKD) or peritoneal-dialysis (PDD-CKD) dose is separately payable. Full setting-by-setting table ↓

How does Venofer's cost compare to other IV iron drugs?

Venofer is $227.00 per 1,000 mg of elemental iron, the least expensive of six Medicare Part B IV irons — a 12x spread separates it from Monoferric's $2,107.70 for the same 1,000 mg. See the full class comparison ↓

Do Medigap Plans A and B cover the Venofer coinsurance?

Plan A and Plan B pay the full Part B coinsurance on this claim, so those patients owe nothing per dose once the $283 deductible is met. Plan K owes $8.31 and Plan L owes $4.16 on the same claim. Full explanation: what every plan letter A–N covers →

How do commercial plan rates for Venofer compare to Medicare?

Aetna's median published rate for J1756 is about $0.23 per mg, close to Medicare's $0.227 and negotiated rather than tied to ASP+6%. Full explanation: how contracted rates are set and why they vary by payer and state →

How do I find the commercial reimbursement rate for Venofer?

Select the payer and the state in the estimator above. It reads that payer’s own published price file for J1756 and returns the median allowed amount for that state, with the sample size it came from. Check a payer →

Sources: CMS ASP pricing files (Q3 2026); Medicare physician fee schedule (96374, 96365, 96366, 99214, national non-facility); Medicare Part B deductible (2026); Medicare Rights Center 2026 Medigap plan benefits chart; 37 commercial payer published price files (Q2 2026); CMS ESRD Prospective Payment System; American Regent AR Assist program terms (venofer.com/arassist); NLM Clinical Table Search Service ICD-10 verification (2026-09-12).

Reviewed September 12, 2026 by Erin Rose, CareCost Estimate founder. Methodology →