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Venofer (J1756) billing units

1 billing unit = 1 mg

200 mg dose → 200 billing units

J1756 · iron sucrose

100 mg/5 mL single-dose vial · JZ when nothing is discarded

Calculate this patient's units ↓

Calculate this patient's billing units

200 mg NDD-CKD · 100 mg HDD-CKD (dialysis-bundled) · 300–400 mg PDD-CKD

200 billing units
200 mg ÷ 1 mg/unit = 200 units
Vials
2 × 100 mg
Discarded drug
0 mg
Modifier
JZ
Check the setting first. A 100 mg dose given during in-center or home hemodialysis is bundled into the facility's ESRD PPS rate — do not build a separate J1756 claim for it. The unit math above only applies to a dose that is separately payable: NDD-CKD, PDD-CKD, or non-CKD iron-deficiency anemia.

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Cost estimate · Original Medicare

Patient owes, 200 mg

$16.63
PlanOriginal Medicare · 37 commercial payers also priced
Deductible met$283 of $283 · out-of-pocket tracked
Drug responsibility (20%)$9.08
Administration (96374)$7.55
Assistance programAR Assist · free drug, uninsured only

Change the payer and the estimate re-prices against that payer's own published rate. The result is a good faith estimate for the patient.


Venofer billing reference

How to calculate Venofer billing units

J1756 bills 1 mg per unit: ordered dose ÷ 1 mg = billing units. A 100 mg dose is 100 units, a 200 mg dose is 200 units, and a 300 mg or 400 mg dose is 300 or 400 units — no rounding and no per-kilogram multiplication for any of the adult regimens.

Venofer ships as a 100 mg/5 mL single-dose vial, so the 100 mg, 200 mg and 300 mg doses each draw whole vials with nothing left over, which is why JZ is the modifier on virtually every adult claim. Only the pediatric 0.5 mg/kg dose (capped at 100 mg) can land between vial sizes and produce a JW waste line.

Medicare pays $0.227 per mg (ASP+6%), effective for claims in Q3 2026 — $45.40 for the 200-unit example above, before the $37.74 administration allowance.

Common Venofer billing-unit examples

DoseBilling unitsVialsModifierSeparately payable?
100 mg (HDD-CKD, given during hemodialysis)1001 × 100 mgJZNo — bundled in ESRD PPS
200 mg (NDD-CKD, standard adult dose)2002 × 100 mgJZYes
300 mg (PDD-CKD, first two doses)3003 × 100 mgJZYes
400 mg (PDD-CKD, third dose)4004 × 100 mgJZYes
Pediatric HDD, 40 kg × 0.5 mg/kg = 20 mg201 × 100 mgJW (80 mg discarded)No — bundled in ESRD PPS
Pediatric HDD, capped at 100 mg1001 × 100 mgJZNo — bundled in ESRD PPS

JW and JZ modifiers for Venofer

JZ — no discarded drug from a single-dose container. JW — discarded drug from a single-dose container, reported on its own claim line. One of the two is required on every separately payable J1756 claim per CMS's July 1, 2023 single-dose container policy.

Standard adult dose (no waste): 200 mg ÷ 1 = 200 units administered. 200 mg ÷ 100 = 2 vials drawn = 200 units drawn. Drawn equals administered, so bill J1756 × 200 JZ · 96374 × 1. The same is true for the 100 mg and 300 mg doses (1 and 3 vials, zero waste) — JZ is the norm on virtually every adult Venofer claim.
Pediatric dose, 40 kg at 0.5 mg/kg (waste, two claim lines): 20 mg ÷ 1 = 20 units administered. 20 mg ÷ 100 = 1 vial drawn = 100 units drawn. 100 − 20 = 80 units discarded, billed on their own JW line: J1756 × 20 · J1756 × 80 JW. This dose is labeled for use during hemodialysis, so in practice it is usually bundled into the ESRD PPS facility rate along with the adult 100 mg HDD-CKD dose — the JW line applies only if the dose is ever billed separately from that bundle.

Venofer administration codes

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96374 is the primary code: the labeled 100 mg and 200 mg doses are a slow IV push over 2–5 minutes. 96365 applies only when the dose is diluted in saline and infused over 15 minutes or more — the NDD-CKD infusion option and the 300 mg PDD-CKD dose — and 96366 pairs with it for the 400 mg PDD-CKD dose, which runs 2.5 hours. Full code definitions live on CPT 96374–96376 and CPT 96365–96366 rather than repeated here.

Vial and code family

Venofer ships in one size: a 100 mg/5 mL (20 mg/mL) single-dose vial, NDC 00517-2340-01. J1756 (“Injection, iron sucrose, 1 mg”) covers iron sucrose from any manufacturer; American Regent's Venofer is the reference product billed under that code. Five other IV iron agents — Ferrlecit, Feraheme, INFeD, Injectafer and Monoferric — are a different molecule each, with their own HCPCS codes and their own unit math; none of them bills under J1756. See the FDA Venofer label for full dosing and administration instructions, or the current Medicare rate for J1756 →.

Frequently asked questions

How many billing units are in a 200 mg dose of Venofer?

200 billing units. Venofer J1756 bills 1 unit per 1 mg, so the dose in mg and the unit count are always the same number.

How many units do I bill for the 100 mg hemodialysis dose?

100 units, if the dose is ever billed separately at all. In practice the 100 mg dose given during in-center or home hemodialysis is bundled into the facility's ESRD PPS rate, so most of the time there is no separate J1756 line to build.

What is the J-code for Venofer?

J1756. It covers iron sucrose from any manufacturer, and American Regent's Venofer is the reference product billed under that code.

Does Venofer require JW or JZ?

JZ on virtually every adult claim — the 100 mg, 200 mg and 300 mg doses each draw whole 100 mg vials with nothing left over. JW only comes up with the pediatric 0.5 mg/kg dose, capped at 100 mg, which rarely fills a whole vial.

What is the most common Venofer billing-unit error?

Billing 2 units for a 200 mg dose because 2 vials were used. J1756 is 1 mg per unit, not 1 vial per unit, so a 200 mg dose is 200 units — billing 2 units instead pays $0.45 rather than $45.40.

Sources

Data current: pricing Q3 2026

Sources: CMS ASP pricing files (Q3 2026); FDA-approved prescribing information (VENOFER label, American Regent); CMS single-dose container JW/JZ policy (effective July 1, 2023); CMS ESRD Prospective Payment System bundling rule (effective January 1, 2011); CPT codebook administration-code guidance.

Reviewed September 12, 2026 by Erin Rose, CareCost Estimate founder. Methodology →