Polatuzumab Vedotin-piiq · Specialty pharmacy
Polivy (J9309) carries a median commercial contracted rate of 95.6 on the Medicare ASP=100 index — 6.9% below the 102.7 typical-acquisition benchmark and 8.3% below the 104.3 Medicare payment line. 57 insurers report contracted rates across 52 states (994 priced cells), covering $188M in modeled Part B spend. It ranks #16 of 25 on the CareCost Buy-and-Bill Risk List, with a risk score of 69.6 out of 100.
Shaded band: 10th–90th percentile across insurers. Darker band: 25th–75th percentile. Solid tick: median. Dashed lines: 100 (Medicare ASP), 102.7 (typical acquisition cost), 104.3 (Medicare payment after sequestration), 93.3 (NADAC-measured acquisition, see below).
All 50 insurers with published rates for this code, ranked highest to lowest. Index is a multiple of Medicare ASP (ASP=100).
Medicare's payment limit for Polivy moved +20.8% between Q1 2022 and Q2 2026. Because contracted rates are set as a multiple of ASP, a rising denominator lifts every contracted rate tied to it.
Solid dots: finalized CMS ASP quarters. Hollow dots: preliminary. Values are the Medicare payment limit (ASP + 6%, pre-sequestration) per billing unit.
| Year | Part B spend | Dosage units (M) |
|---|---|---|
| 2020 | $48M | 0.4 |
| 2021 | $42M | 0.4 |
| 2022 | $66M | 0.6 |
| 2023 | $119M | 1.0 |
| 2024 | $202M | — |
| 2025 | $188M | — |
NADAC-measured acquisition cost for Polivy runs $120.83/unit as of n/a — an acquisition index of 93.3 (ASP = 100).
At the median contracted index of 95.6, that implies a modeled gross margin of +2.3 points per ASP-unit — roughly +$3.12/unit at the latest ASP of $135.48.
Modeled from NADAC acquisition, high confidence — your invoice price governs.
| Highest-paying states | Index | Insurers |
|---|---|---|
| Alaska (AK) | 108.1 | 7 |
| South Dakota (SD) | 104.1 | 8 |
| Iowa (IA) | 104.1 | 8 |
| Nebraska (NE) | 103.8 | 8 |
| Idaho (ID) | 103.5 | 12 |
| Lowest-paying states | Index | Insurers |
|---|---|---|
| Florida (FL) | 95.3 | 34 |
| Louisiana (LA) | 95.2 | 8 |
| Mississippi (MS) | 95.2 | 12 |
| Alabama (AL) | 95.2 | 13 |
At the median contracted rate, this code models a −$6,955 shortfall per $100,000 of acquisition-benchmark drug cost purchased — illustrative modeled margin exposure, not a claim about any single practice's actual reimbursement.
Based on 994 priced contract cells across 57 insurers and 52 states. These are insurers' contracted rates from published machine-readable files — not amounts actually paid on a claim, and not a guarantee of coverage or reimbursement. CareCost Estimate Infusion Reimbursement Index, Issue 01 (Q2 2026), v2.0. CC-BY 4.0.
See also: Krystexxa · Gammagard Liquid · Enhertu · report home · methodology