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Injectafer (J1439) cost and reimbursement per dose

Original Medicare: the patient owes $177.35 for a 750 mg visit

Medicare allows $886.74 for the drug and its administration. The patient owes 20% of it once the Part B deductible is met, and a Medigap plan can take that to $0.

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What sets the amount

Administration (96374) is $37.74 against $849.00 for the drug on the default 750 mg dose — 4.3% of the $886.74 allowed amount, the opposite of an iron sucrose visit, where administration nearly equals the drug. The real trade on this drug is visits, not administration share: matched to the same 1,000 mg of iron, Injectafer's single-dose alternative allows $1,169.74 in one visit against $415.70 for a five-visit iron sucrose course — 2.8x the money for four fewer visits. Injectafer's labeled two-dose course prices a different, larger quantity: $1,773.48 for 1,500 mg across two visits. Full course math and the class comparison: the IV iron class ↓

Medicare allows
$1.132
per unit · ASP+6%, Q3 2026
Part B deductible
$283
in 2026, before the 20% starts
Medigap
$0 with Plans A–G, M, N
Plan K owes $88.67 · Plan L owes $44.34
Commercial
$1.13/mg median (Aetna)
37 payer price files on file
Data current: pricing Q3 2026 · commercial price files Q2 2026 · Part B deductible 2026

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750 mg (two-dose course) and 1,000 mg (single dose) both price a patient 50 kg and over on the 96374 IV push code · under-50 kg dosing is weight-based at 15 mg/kg per dose, two doses at least 7 days apart

Administration

Injectafer has no second administration code on this estimator — the label's diluted-infusion route (at least 15 minutes) bills 96365 instead of 96374, but CPT reports anything documented at 15 minutes or under as a push regardless of which route was intended. A 750 mg push at about 100 mg/min runs roughly 7.5 minutes, so 96374 is what most visits support; only a documented infusion time over 15 minutes justifies 96365.

Include only when a significant, separately identifiable E/M service is performed and documented (modifier 25).

ItemQtyPayer allowsPatient owes
Injectafer (ferric carboxymaltose) J1439750$849.00$169.80
Intravenous push, single drug 963741$37.74$7.55
Total$886.74$177.35
The payer-allows column is what the practice is reimbursed for this claim. The patient-owes column is that patient’s share of it.

Aetna pays its contracted rate ($1.13 per unit, median). What this patient owes depends on their deductible, coinsurance and out-of-pocket position, and on any assistance program.

Medicare's 80% payment is reduced by the 2% sequester; the patient's 20% coinsurance is not affected.

Patient owes
$177.35
20% coinsurance, deductible met

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The estimate above assumes the deductible is already met. Most patients are part-way through theirs for most of the year, and that changes what they owe today.

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What CareCost returns

Original Medicare · Injectafer · 750 mg

$177.35

Patient owes · deductible met

Drug responsibility$169.80
Administration + visit$7.55
With assistanceNo open fund for this diagnosis on Medicare today

Commercial estimates use the payer’s published rate and this patient’s actual benefits.


Injectafer cost reference

How Medicare pays for Injectafer

$1.132 per mg is Part B's ASP+6% rate for Q3 2026. Medicare pays J1439 per 1 mg billing unit — a 750 mg dose is 750 units, and units equal the ordered mg directly, no conversion step. On the default 750 mg dose that is $849.00 for the drug, and the administration line (96374, $37.74) is only 4.3% of the $886.74 allowed amount — nowhere near the near-even split on a cheaper iron. The push (96374–96376) and infusion (96365–96366) code pages carry the full definitions; for Injectafer the only question that matters is whether the documented time crosses 15 minutes, since a 750 mg push at about 100 mg/min runs roughly half that. Full explanation: How Medicare Part B drug cost sharing works →

Common Injectafer doses and Medicare's allowed amount

DoseUnitsMedicare drug allowed
100 mg100$113.20
500 mg500$566.00
750 mg750$849.00
1,000 mg1,000$1,132.00

What a full two-dose course costs

The labeled iron-deficiency-anemia course for a patient 50 kg and over is two 750 mg doses at least 7 days apart — 1,500 mg per course, not an open-ended schedule. Each dose is its own claim, each with its own 96374 administration line:

Cost of the full two-dose course: 2 visits of 750 mg plus 96374 administration.
VisitsDose allowed (2 × $849.00)Administration allowed (2 × $37.74)Course total allowed
2$1,698.00$75.48$1,773.48

Administration is only about 4% of the course total here, unlike a cheaper iron where it runs closer to half the bill. A denied or downcoded 96374 line on either visit still costs the practice $37.74 — real money, but small next to an $849.00 drug line, which is where a pricing error on this drug actually hurts.

Why the estimator defaults to 750 mg, and where heart-failure dosing lives instead

Iron-deficiency anemia and the non-dialysis CKD indication both dose the same way — 750 mg twice, at least 7 days apart, for a patient 50 kg and over — so the estimator's 750 mg default prices either diagnosis without a separate setting. The label also allows a single 15 mg/kg dose up to 1,000 mg for a patient who cannot return for a second visit, and a weight-based 15 mg/kg-per-dose rule from age 1 year for anyone under 50 kg. Those are the three regimens above.

The heart-failure indication is different in kind, not degree: the label sets the dose from a table of weight (under 70 kg or 70 kg and over) crossed with hemoglobin (under 10, 10 to 14, or over 14 to under 15 g/dL), with a 1,000 mg or 500 mg Day 1 dose, a Week 6 dose or none, and 500 mg maintenance doses at weeks 12, 24 and 36 if ferritin or transferrin saturation still qualify. No single number describes it, so it is not one of the estimator's choices — it is priced by looking up the row that matches the patient, not by picking a setting:

Injectafer heart-failure dosing, label Table 1, by weight and hemoglobin.
WeightHemoglobinDay 1Week 6
Under 70 kgUnder 10 g/dL1,000 mg500 mg
Under 70 kg10 to 14 g/dL1,000 mgNone
Under 70 kgOver 14 to under 15 g/dL500 mgNone
70 kg and overUnder 10 g/dL1,000 mg1,000 mg
70 kg and over10 to 14 g/dL1,000 mg500 mg
70 kg and overOver 14 to under 15 g/dL500 mgNone

Maintenance doses of 500 mg at weeks 12, 24 and 36 are added if ferritin is under 100 ng/mL, or 100 to 300 ng/mL with transferrin saturation under 20%. A 1,000 mg Day 1 dose allows $1,132.00 for the drug plus $37.74 for 96374, the same $1,169.74 as the single-dose IDA visit above; a 500 mg dose allows $566.00 plus $37.74. There is no cumulative price for this regimen on this page — it depends on how many maintenance doses a given patient's labs call for, up to 36 weeks.

What each Medigap plan leaves the patient with

For a 750 mg dose with the 96374 IV push administration code, Medicare allows $886.74, and the Part B coinsurance on that is $177.35. Plans A, B, C, D, F, G, M and N cover that coinsurance in full, so those patients owe nothing per dose once the $283 deductible is met; Plan K leaves $88.67 and Plan L $44.34. The single 1,000 mg dose has its own, larger coinsurance: it allows $1,169.74, so 20% of it is $233.95 — more than the $177.35 owed on a 750 mg visit, the same one-bigger-bill-instead-of-two trade as the course total below.

Unlike a drug whose whole claim is smaller than the deductible, a single Injectafer visit ($886.74) is more than three times the $283 Part B deductible, so the deductible is a one-time partial hit rather than a recurring one. Whichever visit in the course happens to land before the deductible is met absorbs the full $283 plus 20% of the remaining $603.74 ($120.75), for $403.75 on that visit; every other visit in the year is a plain $177.35 coinsurance. Across the two-visit course, a patient who has not yet met the deductible pays $403.75 on the first visit and $177.35 on the second, for $581.10 total — against $354.70 if the deductible was already met before the course started.

That is why the month a course starts still matters here, even though the claim itself is large enough that Medigap coverage, not the deductible, decides most of what full-coverage-plan patients owe. See what each Medigap plan (A–N) owes on this claim →

Plan Covers Part B deductible ($283) Covers Part B coinsurance Patient owes, deductible met Patient owes, deductible not met
Plan KNo50%$88.67$343.37
Plan LNo75%$44.34$313.19

Only the letters that leave this patient a balance are listed. The full A–N grid, the high-deductible variants, Plan N’s office-visit carve-out and the MACRA restriction on Plans C and F are at Medigap Plans A–N.

Commercial plans

Commercial payers negotiate their own rate for J1439, not ASP+6% — Aetna's median published rate across the corpus is about $1.13 per mg, close to Medicare's $1.132, putting a 750 mg dose at about $847.50 before benefits. Full explanation: How commercial drug reimbursement works →

Five irons, one job: what 1,000 mg costs and how many visits it takes

Priced per 1,000 mg of elemental iron at Q3 2026 ASP+6%, Injectafer runs about 5x Venofer's price for the same job — the question worth asking is what that difference buys back in visits:

Medicare Part B allowed amount per 1,000 mg of elemental iron, across six IV iron products.
ProductCodePer unitPer 1,000 mg
Ferrlecit (sodium ferric gluconate)J2916$2.197 / 12.5 mg$175.76
Venofer (iron sucrose)J1756$0.227 / mg$227.00
Feraheme (ferumoxytol)Q0138$0.370 / mg$370.00
INFeD (iron dextran)J1750$18.993 / 50 mg$379.86
Injectafer (ferric carboxymaltose)J1439$1.132 / mg$1,132.00
Monoferric (ferric derisomaltose)J1437$21.077 / 10 mg$2,107.70

A 12x spread separates the cheapest and most expensive products in this class for the same 1,000 mg of iron, and Injectafer sits near the top of it: about 5x Venofer's price for the same iron. What Venofer does not buy back is visits — its labeled course for that same 1,000 mg is five separate 200 mg doses, each with its own 96374 line, for a total of $415.70 allowed. Matched to that same 1,000 mg, Injectafer's single-dose alternative allows $1,169.74 in one visit — 2.8x the money, but four fewer visits.

Injectafer's labeled two-dose course prices a different, larger quantity: 1,500 mg across two visits for $1,773.48 allowed, not a like-for-like match to Venofer's 1,000 mg course. The visit count, not the drug, is what a cheaper iron actually saves a payer.

11 of the 16 payers in this corpus make a patient fail another IV iron before they pay for Injectafer; UHC and Independence require failure on two. See how each payer writes that rule → This table compares Medicare allowed amounts only; it is not a clinical recommendation, and no product here is more or less clinically appropriate than another based on price alone.

ASP+6% by quarter

QuarterASP+6% per mg
2025 Q1$1.105
2025 Q2$1.127
2025 Q3$1.144
2025 Q4$1.107
2026 Q1$1.115
2026 Q2$1.103
2026 Q3 (current)$1.132

Patient assistance

American Regent runs the Injectafer Savings Program for commercially insured patients: $50 per dose, with the program paying up to $500 per dose toward the drug, capped at $2,000 and four doses per calendar year. It covers the drug only — the $37.74 96374 charge is billed and owed separately, so a commercial patient using the card still sees an administration line the card does not touch. Medicare, Medicaid, TRICARE and federal-plan patients are excluded from the card; DS Access Central offers free drug to uninsured patients or those in a coverage gap. Full assistance program details →

ICD-10 codes

D50.9 (iron deficiency anemia, unspecified) is the reference code on this page; the same iron-deficiency-anemia indication also bills D50.0 or D50.8 when the chart documents which one. D63.1 (anemia in chronic kidney disease) is the primary code for the non-dialysis CKD indication, paired with a CKD stage or dialysis-status code from N18.30 through N18.5. The heart-failure indication's primary code is E61.1 (iron deficiency), paired with a billable I50 heart- failure child code such as I50.22 or I50.32.

A three-character heart-failure category code by itself is not billable, and neither is the three-character iron-deficiency-anemia category on its own — both need the added digit(s) that make them a specific, billable code.

Frequently asked questions

How much does Medicare pay for Injectafer?

$1.132 per mg for Q3 2026 (ASP+6%). The labeled 750 mg dose needs 750 units, so Medicare's allowed drug amount is $849.00.

What does a Medicare patient owe for a 750 mg Injectafer visit?

For a 750 mg dose with the 96374 IV push administration code, Medicare allows $886.74 and the patient's 20% coinsurance is $177.35 after the Part B deductible is met. What each Medigap plan leaves on this claim ↓

Why does the single 1,000 mg dose cost more per visit but less for the whole course?

One 1,000 mg visit allows $1,169.74, more than a single 750 mg visit, because it is a bigger dose given at once. But it replaces the two-dose course entirely: the full course allows $1,169.74 in one visit against $1,773.48 across two 750 mg visits, a savings of $566.00 of drug and one $37.74 administration charge.

Does the Injectafer Savings Program cover the administration fee?

No. The program pays up to $500 per dose toward the $50-per-dose commercial copay on the drug itself; the $37.74 charge for 96374 is billed separately and the card does not touch it. Full assistance program details →

What does Medicare allowed amount mean on this page?

It is the total Medicare recognizes for the claim, not what the practice charges: $849.00 for the drug at $1.132 per mg plus $37.74 for the 96374 push, $886.74 for a 750 mg visit. The patient's coinsurance is 20% of that allowed number.

How does Injectafer's cost compare to other IV iron drugs?

Injectafer is $1,132.00 per 1,000 mg of elemental iron, roughly five times Venofer's $227.00 for the same 1,000 mg — but Venofer's course needs five visits to Injectafer's one or two. See the full class comparison ↓

How do I find the commercial reimbursement rate for Injectafer?

Select the payer and the state in the estimator above. It reads that payer’s own published price file for J1439 (37 of 37 payer files carry a rate) and returns the median allowed amount for that state, with the sample size it came from. Check a payer →

Sources: CMS ASP pricing files (Q3 2026); Medicare physician fee schedule (96374, 96365, 96366, 99214, national non-facility); Medicare Part B deductible (2026); Medicare Rights Center 2026 Medigap plan benefits chart; 37 commercial payer published price files (Q2 2026); DailyMed label (setid 517b4a19-45b3-4286-9f6a-ced4e10447de, Revised 08/2026); NLM Clinical Table Search Service ICD-10 verification (2026-09-19); American Regent Injectafer Savings Program and DS Access Central program terms (injectafercopay.com, ar-assist.com).

Reviewed September 19, 2026 by Erin Rose, CareCost Estimate founder. Methodology →