CareCost CareCost Estimate

Eylea copay assistance programs

With commercial insurance: EYLEA4U Commercial Copay Card Program — as little as $0, up to $20,000 per rolling year. With Medicare: the Eylea card can’t be used. HealthWell Foundation – AMD and Retinal Vascular Diseases is closed as of September 29, 2026.

Copay program checked September 28, 2026 · Source ↗

See what this patient owes after assistance →

9 assistance programs for Eylea patients · 2 open today

Two Regeneron programs cover Eylea: one for commercial insurance, one for uninsured patients. Nine foundation funds are on file. The Assistance Fund's Macular Degeneration fund and eight more funds are on file; check each fund's current status on the funds list. This page’s fund cards update automatically if one reopens.

Select the patient's insurance to see which programs may apply.

Current status · Award amounts · Eligibility · Direct application links

Eylea assistance, in the order you will use it

Copay program · EYLEA4U Commercial Copay Card Program

Open
Who qualifiesCommercial or private insurance that covers EYLEA HD and/or EYLEA, FDA-approved indication, US resident. No income requirement. Medicare, Medicaid, VA, DoD, TRICARE excluded.
What it pays forThe Eylea card pays for the drug and the administration (infusion or injection) fee.
Yearly max$20,000 per rolling year (product) + $1,000 per rolling year (administration, CPT 67028); MA and RI residents not eligible for administration assistance; supplies not covered
Clinic-billed (medical benefit) claimsYes. Submitted by: the provider or the patient.
How to submitFax to 1-888-335-3264. Required: patient name, DOB, DOS; diagnosis code; J0177/J0178 amount billed/allowed/paid/patient responsibility; 67028 amounts; patient address for payment. Typically from an EOB, CMS-1450/CMS-1500, receipt of payment or physician statement.
Phone1-855-395-3248

Checked September 28, 2026 · Source 1 ↗ · Source 2 ↗

Free-drug program · Regeneron Patient Assistance

Open
Who qualifiesIncome: Financial need based on annual household income; no income figure is published. Call the program to check. Insurance: Must be underinsured, uninsured, or not covered for EYLEA HD/EYLEA; must be enrolled in EYLEA4U; Medicare FFS and Medicare Advantage patients can qualify (enrolled to end of calendar year); reapply annually.
Phone1-855-395-3248

Checked September 28, 2026 · Source 1 ↗ · Source 2 ↗

If the patient has Medicare

Eylea’s card can’t be used with Medicare. These funds may help. They open and close with donations, so call before telling a Eylea patient no.

The Assistance Fund (TAF) – Macular DegenerationNot confirmed, call lists Eylea
Checked September 28, 2026 · Source ↗
HealthWell Foundation – AMD and Retinal Vascular DiseasesClosed $4,000 lists Eylea
Checked September 29, 2026 · Source ↗
TotalAssist (Patient Advocate Foundation) – Macular degeneration and related diseasesClosed $4,600 lists Eylea
Checked September 28, 2026 · Source ↗
TotalAssist (Patient Advocate Foundation) – Diabetic macular edema (DME)Closed $4,500 lists Eylea
Checked September 28, 2026 · Source ↗
TotalAssist (Patient Advocate Foundation) – Retinal vein occlusion (RVO)Closed $4,600 lists Eylea
Checked September 28, 2026 · Source ↗
TotalAssist (Patient Advocate Foundation) – Diabetic retinopathy (DR)Closed $4,500 lists Eylea
Checked September 28, 2026 · Source ↗
Good Days – Vascular and Neovascular Retinal DiseaseClosed lists Eylea
Checked September 29, 2026 · Source ↗

Support hub · EYLEA4U

What they doBenefit verification (60 seconds electronic, up to 48 hours by fax), prior authorization support, appeals support, claims support, copay card, PAP, ePortal E4Ueportal.com, field Reimbursement Business Managers
Phone1-855-395-3248 Option 4 (reimbursement and patient assistance)

Checked September 28, 2026 · Source 1 ↗ · Source 2 ↗

3 programs match this patient · 1 open · 1 more if coverage falls short

Eylea · Wet AMD · Commercial insurance

EYLEA4U Commercial Copay Card ProgramOpen

Eligible patients may pay $0

Potential benefit$0 · $20,000/year annual maximum applies
InsuranceCommercial ✓ · Government insurance ✗
DiagnosisWet AMD ✓
IncomeNo income requirement
Phone1-855-395-3248
Current statusOpen
Last verifiedSeptember 28, 2026

Calculate this patient’s cost with this program ↓

Calculate this patient’s cost with EYLEA4U Commercial Copay Card Program

Assistance

Free · No credit card · No sales call

Run the estimate with assistance, without assistance, or both side by side.

What CareCost shows

Example · Eylea · 2 mg · 2 units · commercial plan · deductible met · 20% coinsurance · allowed amounts at the Medicare reference rate

Without assistanceWith EYLEA4U Commercial Copay Card Program
Drug responsibility$288.90$0.00
Administration (67028)$22.85$0.00
Patient owes$311.75$0.00

Estimated patient savings: $311.75

CareCost calculates the drug and administration lines using the patient’s payer rate and benefits; this example uses the Medicare rate as a reference.

3 more Eylea programs for this patient

The Assistance Fund — Macular DegenerationWaitlist

Maximum award See program

The Assistance Fund fund for government-insured patients with Diagnosis of macular degeneration with prescription for FDA-approved treatment.

Potential benefitUp to See program
InsuranceCommercial ✓ · Medicare ✓ · Medicaid ✓
DiagnosisWet AMD ✓
IncomeCall the foundation to check who qualifies.
Phone855-308-0361
Current statusWaitlist

Calculate this patient’s cost if this fund reopens ↓

HealthWell Foundation — Macular Degeneration (Wet and Dry)Closed

Maximum award $4,000

HealthWell Foundation fund for government-insured patients with Macular Degeneration (Wet and Dry) (confirmed diagnosis).

Potential benefitUp to $4,000/year
InsuranceCommercial ✓ · Medicare ✓ · Medicaid ✓ · TRICARE ✓
DiagnosisWet AMD ✓
IncomeCall the foundation to check who qualifies.
Phone800-675-8416
Current statusClosed to new applications
Last verifiedSeptember 29, 2026

Calculate this patient’s cost if this fund reopens ↓

Also available if this patient’s coverage falls short

Regeneron Patient AssistanceIf underinsured

Free Regeneron Patient Assistance for eligible patients

Potential benefitFree drug — no limit
InsuranceUninsured ✓ · Underinsured ✓ · Medicare ✓ · Commercial ✗ · Medicaid ✗
DiagnosisWet AMD ✓
IncomeNo income limit is published. Call the program to check.
Covers administrationNo — the injection fee is not covered
Phone1-855-395-3248
Current statusOpen
Last verifiedSeptember 28, 2026

Calculate this patient’s cost with this program ↓

Other Eylea assistance programs

Change the diagnosis to see only the programs that apply to your patient.

Diabetic macular edema5 programsCheck current programs →
Macular edema after RVO3 programsCheck current programs →
Diabetic retinopathy4 programsCheck current programs →
Retinopathy of prematurity2 programsCheck current programs →
Neurodegenerative Retinal Disease, Inherited Retinal Disease (IRD)2 funds · 0 open
Eylea is not interchangeable with the other anti-VEGF products that treat the same conditions. Eylea HD (J0177, 8 mg, Regeneron), Pavblu (Q5147, Amgen, the aflibercept biosimilar), Vabysmo (J2777, Genentech), Lucentis (J2778, Genentech), Cimerli (Q5128, Sandoz), Byooviz (Q5124, Biogen / Samsung Bioepis), Beovu (J0179, Novartis) and off-label Avastin (J9035, Genentech) are separate products under separate HCPCS codes. The EYLEA4U Commercial Copay Card Program and Regeneron Patient Assistance apply only to a patient actually prescribed and billed Eylea (J0178). Most aflibercept payers direct a new patient to another product first (22 of 28 in CareCost’s coverage corpus require a documented trial, most often of repackaged bevacizumab), and if the payer’s preferred-product policy lands the patient on one of the other products instead, that manufacturer runs its own separate assistance program, listed below. Confirm the product actually administered before applying to a Regeneron program.

One assistance search. One patient estimate.

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How Eylea assistance works

Commercial insurance: Eligible commercially insured patients may qualify for the EYLEA4U Commercial Copay Card Program. Eligible patients may pay as little as $0 per treatment toward the Eylea drug charge, up to $20,000 a year; the card also pays up to $1,000 a year toward the injection procedure (not in MA or RI), and does not cover supplies or physician fees. It excludes Medicare, Medicaid and other government insurance. View current program ↑

How the lines work: An Eylea visit produces two charges: a drug line under J0178, 2 units per eye, and a procedure line for the injection itself, 67028, reported per eye (RT or LT, or once with modifier 50 when both eyes are treated at the same visit). Each line carries its own patient share. The EYLEA4U Commercial Copay Card Program pays the drug line’s share only, never the 67028 charge.

Medicare: Manufacturer copay assistance is not available to patients using Medicare to pay for Eylea; the EYLEA4U Commercial Copay Card Program explicitly excludes Medicare, Medicaid and other government plans. What exists instead is a Medigap policy that picks up the Part B coinsurance (see the cost page for the math), Medicaid dual eligibility where it applies, a foundation fund when one reopens, and Regeneron Patient Assistance for patients who are uninsured. View current options ↑

The foundation funds: Nine funds are on file for Eylea. The Assistance Fund's Macular Degeneration fund is on file; check each fund's current status on the funds list. The other eight are HealthWell Foundation's Macular Degeneration fund (up to $4,000 a year), Good Days' two retinal-disease funds, and five TotalAssist eye funds; check each fund's current status on the funds list. This page’s fund cards update automatically when one reopens.

Uninsured: Regeneron Patient Assistance provides Eylea at no cost to qualifying uninsured patients, patients whose coverage falls short and some Medicare patients who meet the program's rules who meet the program's income rules. It ships the drug free to the practice; it does not cover the injection procedure or office-visit fees, so the practice still bills the patient for the 67028 charge, or writes it off. Check today’s status ↑

Why fund status matters: Manufacturer programs can change between: OPEN Accepting applications now · WAITLIST Not enrolling immediately · CLOSED Not accepting new applications. Every CareCost program card shows the status and the date it was verified.

Why the product name matters: Eylea, Eylea HD, Pavblu, Vabysmo, Lucentis, Cimerli, Byooviz and Beovu treat overlapping conditions but are separate products under separate HCPCS codes, each with its own manufacturer and its own assistance program. Confirm the product actually prescribed and billed before applying to a Regeneron program.

Frequently asked questions

Is there an Eylea copay card?

Yes. The EYLEA4U Commercial Copay Card Program is Regeneron’s current commercial-insurance program. Eligible patients may pay as little as $0 per treatment toward the Eylea drug charge, up to $20,000 a year, plus up to $1,000 a year toward the injection procedure (not in MA or RI). Apply / Enroll on EYLEA4U Commercial Copay Card Program ↗ Calculate cost with the program →

Does EYLEA4U cover the injection fee?

Partly. The EYLEA4U Commercial Copay Card Program covers the drug charge (J0178) and pays up to $1,000 a year toward the injection procedure, 67028 per eye (RT or LT, or once with modifier 50 for both eyes). Patients in MA and RI cannot use the administration benefit. It does not cover supplies or a separate office-visit copay. View current program ↑

Can Medicare patients get Eylea for free?

No. The EYLEA4U Commercial Copay Card Program excludes Medicare, Medicaid and other government insurance. A Medicare patient’s options are a Medigap policy that picks up the Part B coinsurance, Medicaid dual eligibility where it applies, a foundation fund if one reopens, or Regeneron Patient Assistance for patients who are uninsured. See Medicare cost math →

Is there a foundation fund for Eylea?

Nine are on file. The Assistance Fund's Macular Degeneration fund is on file; check each fund's current status on the funds list. The other eight are HealthWell Foundation's Macular Degeneration fund (up to $4,000 a year), Good Days' two retinal-disease funds, and five TotalAssist eye funds; check each fund's current status on the funds list. This page’s fund cards update automatically when one reopens.

How do you apply for Regeneron Patient Assistance?

Apply at Eylea.us ↗ or call 1-855-395-3248; Regeneron Patient Assistance then provides Eylea at no cost to qualifying uninsured patients, patients whose coverage falls short and some Medicare patients who meet the program's rules who meet the program's income rules. It ships the drug free to the practice but does not cover the injection procedure or office-visit fees. The practice still bills the patient, or writes off, the 67028 charge.

What if the patient’s plan denied Eylea?

A claim the payer turned down leaves no approved amount for a copay program to reduce; the EYLEA4U Commercial Copay Card Program applies only to an approved claim, and it is not an appeals program. 22 of the 28 payers in CareCost’s aflibercept coverage corpus require a documented trial of another product first, most often repackaged bevacizumab. Check the payer’s prerequisites before assuming the claim will be approved. Check coverage requirements →

Assistance for the other products in this family

Eylea shares its class with Eylea HD (J0177, Regeneron), Pavblu (Q5147, Amgen), Vabysmo (J2777, Genentech), Lucentis (J2778, Genentech), Cimerli (Q5128, Sandoz), Byooviz (Q5124, Biogen / Samsung Bioepis), Beovu (J0179, Novartis), billed under their own codes with their own manufacturer programs. The programs above apply to Eylea only. If the payer requires the other product instead, use that manufacturer’s program below.

Each card is the program record on file, verified on the date it shows. None of them pays the administration line. Pavblu has no program record on file.

Eylea HD (J0177) · RegeneronOpen

EYLEA4U Commercial Copay Card Program (Eylea HD)

Applies whenPatient is on Eylea HD, not Eylea
BenefitCopay assistance: $20,000/year
InsuranceCommercial
Current statusOpen
Last verifiedApril 8, 2026
Eylea HD (J0177) · RegeneronOpen

EYLEA4U Patient Assistance Program (Eylea HD)

Applies whenPatient is on Eylea HD, not Eylea
BenefitFree drug — limit not on file
InsuranceUninsured
Current statusOpen
Last verifiedApril 8, 2026
Vabysmo (J2777) · GenentechOpen

Genentech Ophthalmology Co-pay Program

Applies whenPatient is on Vabysmo, not Eylea
BenefitCopay assistance: $15,000/year
InsuranceCommercial
Current statusOpen
Last verifiedMay 28, 2026
Vabysmo (J2777) · GenentechOpen

Genentech Patient Foundation (Free Drug)

Applies whenPatient is on Vabysmo, not Eylea
BenefitFree drug — no limit
InsuranceUninsured
Current statusOpen
Last verifiedMay 28, 2026
Lucentis (J2778) · GenentechOpen

Genentech Patient Foundation

Applies whenPatient is on Lucentis, not Eylea
BenefitFree drug — no limit
InsuranceUninsured
Current statusOpen
Last verifiedJuly 16, 2026
Lucentis (J2778) · GenentechOpen

Genentech Ophthalmology Co-pay Program

Applies whenPatient is on Lucentis, not Eylea
BenefitCopay assistance: $15,000/year
InsuranceCommercial
Current statusOpen
Last verifiedMarch 22, 2026
Cimerli (Q5128) · SandozClosed

Cimerli Solutions Co-Pay Program

Applies whenPatient is on Cimerli, not Eylea
BenefitCopay assistance: See program
InsuranceCommercial
Current statusClosed
Last verifiedMay 28, 2026
Byooviz (Q5124) · Biogen / Samsung BioepisClosed

Biogen Copay Program for Byooviz

Applies whenPatient is on Byooviz, not Eylea
BenefitCopay assistance: See program
InsuranceCommercial
Current statusClosed
Last verifiedJune 14, 2026
Beovu (J0179) · NovartisClosed

Beovu Universal Co-Pay Program

Applies whenPatient is on Beovu, not Eylea
BenefitCopay assistance: $15,000/year
InsuranceCommercial
Current statusClosed
Last verifiedJune 14, 2026
Beovu (J0179) · NovartisOpen

Novartis Patient Assistance Foundation (Beovu)

Applies whenPatient is on Beovu, not Eylea
BenefitFree drug — enrollment period applies
InsuranceUninsured · Medicare
Current statusOpen
Last verifiedMay 2, 2026

Sources

Data current: programs verified Sep 29, 2026

EYLEA4U Commercial Copay Card Program · Regeneron Patient Assistance · HealthWell Foundation Macular Degeneration (Wet and Dry) · Good Days Neurodegenerative Retinal Disease · Good Days Vascular and Neovascular Retinal Disease. Every program links directly to its official source or application page.

Last program check: .

Reviewed September 20, 2026 by Erin Rose, CareCost Estimate founder. Methodology →