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Darzalex Faspro (J9144) billing units

1 billing unit = 10 mg

1,800 mg dose → 180 billing units

J9144 · daratumumab and hyaluronidase-fihj

1,800 mg/30,000 units single-dose vial · JZ on every claim

Calculate this patient's units ↓

Calculate this patient's billing units

1,800 mg subcutaneously into the abdomen over 3 to 5 minutes · the same dose on every regimen -- only the interval between doses changes

180 billing units
1,800 mg ÷ 10 mg/unit = 180 units
Vials
1 × 1,800 mg
Discarded drug
0 mg
Modifier
JZ
Common error: J9144 is 10 mg per unit -- not 1 mg and not 1 vial. Billing 1,800 units for the 1,800 mg dose asks Medicare to allow $104,351.40 instead of $10,435.14, a tenfold overpayment request. Billing 1 unit for the single vial asks for $57.97. The correct claim is 180 units.
Claim line
J9144 × 180 JZ
Administration: 96401 × 1

Next step for this Darzalex Faspro claim

Darzalex Faspro · 200 billing units carry straight into the claim.

Claim Check builds the whole visit — J9144 units, the administration line, the modifiers and the Medicare allowed amount — and prices it against your payer's rate. The estimate turns the same visit into what the patient owes.

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Cost estimate · Original Medicare

Patient owes, 1800 mg

$2,083.13
PlanOriginal Medicare · 37 commercial payers also priced
Deductible met$283 of $283 · out-of-pocket tracked
Drug responsibility (19.8% drug / 20% admin)$2,068.77
Administration (96401)$14.36
Copay programJanssen CarePath (withMe Savings Program) · $5 per dose on commercial plans

Change the payer and the estimate re-prices against that payer's own published rate. The result is a good faith estimate for the patient.


Darzalex Faspro billing reference

How to calculate Darzalex Faspro billing units

Darzalex Faspro J9144 is billed in units of 10 mg: ordered dose ÷ 10 mg = billing units. The labeled dose is a flat 1,800 mg for every regimen and every indication, so the calculation has no per-kilogram multiplication and nothing to round -- 1,800 mg ÷ 10 mg = 180 billing units, every time.

Darzalex Faspro ships as a 1,800 mg daratumumab / 30,000-unit hyaluronidase-fihj single-dose vial in 15 mL, sized to match the labeled dose exactly, so the amount drawn (1,800 mg) equals the amount administered (1,800 mg) with nothing left over. That is why JZ (no drug discarded) is the modifier on every Darzalex Faspro claim -- unlike a multi-dose-vial drug, there is no per-vial waste math to do.

Medicare pays $57.973 per 10 mg (ASP+6%), effective for claims in Q4 2026 — $10,435.14 for the 180-unit dose above.

Billing units by product

ProductHCPCSDoseBilling units
Darzalex Faspro (subcutaneous)J91441,800 mg180
Darzalex (IV, 16 mg/kg at 80 kg)J91451,280 mg128

IV Darzalex doses by weight (16 mg/kg), so its unit count moves with the patient; Darzalex Faspro's 1,800 mg dose is fixed regardless of weight. Both bill 10 mg per unit on their own code -- shown here for unit basis, not as a substitution: the two are different formulations of the same molecule, billed under different HCPCS codes and different administration codes.

JW and JZ modifiers for Darzalex Faspro

JZ — no discarded drug from the single-dose vial. JW — discarded drug, reported on its own claim line. One of the two is required on every J9144 claim per CMS's July 1, 2023 single-dose container policy.

Standard dose (no waste): 1,800 mg ÷ 10 = 180 units administered. 1,800 mg ÷ 1,800 = 1 vial drawn = 180 units drawn. Drawn equals administered, so bill J9144 × 180 JZ · 96401 × 1. This is the case on every Darzalex Faspro claim, because the labeled dose is the same 1,800 mg on every regimen and the single-dose vial is sized to match it exactly.

There is no JW scenario for this product on label: every regimen doses the same 1,800 mg, so the drawn amount and the administered amount are always identical. JW would only arise if a claim documented less than the full vial administered -- a dose reduction or a discontinued injection -- which the label does not describe for any indication.

Darzalex Faspro administration code: 96401

Darzalex Faspro is injected subcutaneously into the abdomen over 3 to 5 minutes, billed with 96401 (chemotherapy administration, subcutaneous or intramuscular, non-hormonal anti-neoplastic), which pays $71.81. 96413 and 96415 (chemotherapy infusion administration) never apply to J9144 -- those codes belong to the infused product, Darzalex (J9145), which runs over 3 to 7 hours.

Pre-medication is required 1 to 3 hours before every dose -- acetaminophen, an antihistamine such as diphenhydramine, and a corticosteroid -- plus a post-injection corticosteroid per the label. Bill each on its own claim line under its own code; this reference does not assign codes to the pre-medications themselves.

Show administration codes ▾

96401 is the only administration code this reference uses for Darzalex Faspro. There is no initial-hour or additional-hour split to report, because the injection is not an infusion -- the entire visit runs a few minutes, not hours.

Same billing units, every regimen

Darzalex Faspro has nine labeled regimens across multiple myeloma and light chain (AL) amyloidosis, and every one of them doses the same 1,800 mg. What changes between regimens is the calendar between doses -- the claim line never does.

4-week regimens and monotherapy, year one:
Weeks 1–8: weekly (8 doses)
Weeks 9–24: every 2 weeks (8 doses)
Weeks 25–52: every 4 weeks (7 doses)
Total: 23 doses, every one J9144 × 180 JZ · 96401 × 1
RegimenScheduleUnits per visit
4-week regimens & monotherapyWeekly × 8, every 2 weeks × 8, then every 4 weeks180
VMP (6-week cycle)Weekly × 6, every 3 weeks × 16, then every 4 weeks180
VTd/VRd (around transplant)Weekly × 8, every 2 weeks × 4, transplant, every 2 weeks × 4180
3-week regimensWeekly, then every 3 weeks to week 24, then every 4 weeks180
High-risk smoldering myelomaWeekly × 8, every 2 weeks × 8, then every 4 weeks, capped at 39 cycles180
AL amyloidosis (D-VCd)Weekly × 8, every 2 weeks × 8, then every 4 weeks, capped at 2 years180

Confirm the regimen before the first claim -- the schedule differs by indication and by combination drug, but the dose, the vial and the units never do.

Vial size and form

Darzalex Faspro is supplied as a 1,800 mg daratumumab and 30,000 units hyaluronidase-fihj single-dose vial in 15 mL (120 mg/mL) — there is no other size. NDC 57894-503-01, Janssen Biotech. See the FDA-approved Darzalex Faspro prescribing information (BLA 761145) for the full dosing and administration table.

Code family

J9144 is the subcutaneous daratumumab-and-hyaluronidase code. The IV form of the same molecule, Darzalex, bills under a separate code, J9145, dosed by weight (16 mg/kg) instead of flat, and administered by infusion (96413 or 96415) instead of injection (96401).

See the HCPCS hub for coding across the family. The Medicare rate for every quarter is on the cost page →

Frequently asked questions

How many billing units are in a 1,800 mg dose of Darzalex Faspro?

180 billing units. Darzalex Faspro J9144 bills 1 unit per 10 mg, so the 1,800 mg labeled dose is always 180 units.

What is the J-code for Darzalex Faspro?

J9144. The IV form of the same molecule, Darzalex, bills under a different code, J9145, at a weight-based dose instead of a flat one, so the two are never interchangeable on a claim.

Does Darzalex Faspro require JW or JZ?

JZ on every claim. The 1,800 mg dose exactly fills the single-dose 1,800 mg vial on every regimen, so nothing is left over to discard — there is no JW scenario for this product on label.

Which administration code applies, 96401 or 96413?

96401, always. Darzalex Faspro is a subcutaneous injection, not an infusion, so 96413 and 96415 never apply — those codes belong to the IV product, Darzalex (J9145).

Are the pre-medications billed with Darzalex Faspro?

Yes, on their own claim lines. The label requires acetaminophen, an antihistamine and a corticosteroid 1 to 3 hours before every dose, plus a post-injection corticosteroid — each billed under its own code, separate from the J9144 drug line and the 96401 administration line.

What is the Q4 2026 Medicare reimbursement for J9144?

$57.973 per 10 mg (ASP+6%), effective for claims in Q4 2026 — $10,435.14 for the standard 1,800 mg (180-unit) dose.

Sources

Data current: pricing Q4 2026

Sources: CMS ASP pricing files (Q4 2026); Medicare physician fee schedule (96401, national non-facility); FDA-approved prescribing information (Darzalex Faspro label, Janssen Biotech, BLA 761145, Revised 1/2026); CMS single-dose container JW/JZ policy (effective July 1, 2023); CPT codebook administration-code guidance.

Reviewed September 19, 2026 by Erin Rose, CareCost Estimate founder. Methodology →