ICD-10 — prostate cancer
| Code | For |
C61 | Malignant neoplasm of prostate (primary — required) |
C77.5 | Pelvic nodal mets |
C79.51 | Bone mets (Firmagon-preferred scenario) |
C79.52 | Bone marrow mets |
R97.21 | Rising PSA post-treatment |
Z19.1 / Z19.2 | Hormone sensitive / resistant status |
FDA-approved only for advanced prostate cancer. Off-label use will not have an applicable C-code.
Payer requirements (May 2026)
| Payer | PA | Step / Notes |
| UnitedHealthcare | Yes | Some plans require GnRH agonist trial first; bypass with flare-vulnerable docs |
| Aetna | Yes | Baseline T + PSA + ECG required |
| BCBS plans | Yes | Aligned with NCCN Prostate Ca guidelines |
| Medicare LCDs | No PA | Coverage for FDA-approved indication w/ C61 |
Document flare-avoidance rationale (bone mets, spinal cord compression risk, urinary obstruction) to bypass agonist-first step therapy.
Medicare reimbursement (Q2 2026)
| Field | Value |
| ASP + 6% | $4.458 / mg (effective 4/1 – 6/30/2026) |
| 240 mg loading | $1,069.92 (240 × $4.458) |
| 80 mg monthly | $356.64 (80 × $4.458) |
| Year-1 total (1 load + 11 maint) | ~$4,993 |
Site of care
| Setting | POS | Notes |
| Urology / oncology office | 11 | Preferred — SC injection, no chair time |
| Ambulatory infusion suite | 49 | Acceptable |
| Hospital outpatient | 19/22 | Disfavored for routine maintenance |
| Patient home | 12 | Uncommon — reconstitution complexity |
Patient assistance — Ferring
- Phone: 1-888-FERRING (1-888-337-7464)
- Firmagon Co-pay Program: commercial copay support (excludes Medicare/Medicaid/federal)
- Patient Assistance: free product for uninsured/underinsured
- Medicare patients: refer to PAN, HealthWell, CancerCare, PAF
- Web: firmagon.com
W&P (no Boxed warning): injection-site reactions ~40% (visible nodule lasting weeks — the most-noticed AE), QT/QTc prolongation (baseline + ongoing ECG), hepatic dysfunction (LFT monitoring), hot flashes, decreased bone density (long-term).
Pending SME review. Staff-authored from FDA, CMS, Ferring, payer, NCCN/AUA sources. Verify high-stakes claims at the linked sources.